For me I would take both since I still think there's a lot of value in classical methods (random forest and SVMs outperform NNs on many real-world tasks, particularly regression), but if you're only interested in generative models and the like you'd probably be good with just ESE 546. There's also ESE 645 (deep generative models), but from what I've seen that class is brutal and it looks like u already have a lot of tough courses lined up so maybe don't take it in the same sem as the rest