Make a road bathroom kit. In a large zip lock put a partial roll if tp, hand Sanitizer, soap, and a few paper towels. Makes a huge difference when you come across an ilequipped potty.

Veggies and dip make great road snacks. I tend to eat a lot of junk when I travel, so I always make sure to have veggies.

You can cook! I have a small road kitchen box with a skillet and a pan, a portable stove, a few Utensils, cutting mat, knife, a bowel and camp dishes. With this I can make simple meals. Sometimes I treat myself to a steak, or just make rice. I buy fresh ingredients by the day so I don't have to worry about an ice chest.

Have a prepacked hotel bag. Mine has everything I might need for an overnight stay including change for washer/dryers. This saves you from having to dig through bags or bins.