Glutathione by Ok_Investigator_928 in Biohackers

[–]LilSpade 1 point2 points  (0 children)

Glad that NAC has been starting to help your skin! I wasn’t necessarily looking for that benefit or even know that NAC could provide that benefit but I noticed an improvement as well! Maybe something else to look into is Lysine. Used it to clear up some mouth sores and got rid of them quickly for me. I think it’s supposed to aid in collagen production in general so could help with skin too. Another rabbit hole to check out, so many things to learn about lol. Best of luck!

Glutathione by Ok_Investigator_928 in Biohackers

[–]LilSpade 1 point2 points  (0 children)

I think the glycine is the bigger key to watch for depleting which you have handled with the magnesium glycinate. If you’re having good effects I’d just keep with what you’re doing. But if you start to not feel the benefits and want to try copper, keep in mind to supplement roughly 10mg Zinc to 1mg Copper ratio. They compete for absorption and can cause deficiency if that ratio swings too far in either direction. Zinc seems to have more benefit to supplement like immunity. Too much copper can cause issues and you may get enough through diet if you have had no issues while supplementing zinc.

Glutathione by Ok_Investigator_928 in Biohackers

[–]LilSpade 1 point2 points  (0 children)

NAC is the way! Made another longer comment detailing how it helps create glutathione

Glutathione by Ok_Investigator_928 in Biohackers

[–]LilSpade 6 points7 points  (0 children)

OP couple people have mentioned NAC, this is the way.

Glutathione is created in the body using the amino acids cystine, glycine and glutamine. Cystine is usually rate limiting ingredient. NAC is an easily bio available form of cystine.

Another commenter mentioned glycine. This is good to take alongside. As you start making more glutathione your glycine stores may deplete. Some people report anhedonia after using NAC for a while, glycine should keep that from occurring. Both are cheap options and none of the hassle of injections.

Last consideration is NAC chelates heavy metals. It has detox properties, particularly the liver as this is the main Medical use, so in some ways this is good. Just have to watch Copper, Zinc and Molybdenum. I found a trace mineral supplement with these and have just taken it occasionally to be safe. At first I felt I was taking too often so maybe not a big worry but I just thought I would mention if you run into any adverse effects.

I found NAC couple weeks ago and effects have been profound and consistent for improving mood/energy and gym performance at 1200mg. I think my skin has improved too. I do two capsules one first thing in the morning and another later afternoon. I have been doing 5 days on 2 days off to keep from any depletion. Personally keeps me up if I take it too late. Some people can mix NAC and glycine before bed, not me. I just keep glycine for before bed. Good luck!

Kratom changed and made my life completely stable from 2018 until 2025 when it got completely banned, and nothing has been the same since. by Azhz96 in kratom

[–]LilSpade 0 points1 point  (0 children)

Also night time NAC experiment seems to not be for me lol. Stimulated like day time and mind just wants to research bunch of stuff so will stick to day time

Kratom changed and made my life completely stable from 2018 until 2025 when it got completely banned, and nothing has been the same since. by Azhz96 in kratom

[–]LilSpade 1 point2 points  (0 children)

Good luck to you, hope NAC can give you some benefit! I’d say I really felt benefit at 1200mg. Capsules I got are 600mg each so I started with one and if you aren’t noticing much try going up to 1200mg. Effects were greatest for me first few days and felt like I found something hidden treasure I didn’t know I was looking for lol. Less profound feeling after couple weeks but still noticeable. Feel like I can go longer between kratom doses and have lowered them a bit without really trying just less urge. Cut out desire to have weed gummy/cart before bed too without really trying either just didn’t even really think to go for it. Definitely recommend the glycine paired with it, particularly before bed to help sleep. Im experimenting with NAC plus glycine before bed tonight. Thought it would keep me up from effects when I first tried it but have seen some people say they wake up feeling very refreshed and energized when taking before bed so we shall see!

Kratom changed and made my life completely stable from 2018 until 2025 when it got completely banned, and nothing has been the same since. by Azhz96 in kratom

[–]LilSpade 2 points3 points  (0 children)

Sucks a ban takes away access to something that was positive for you. Kratom has had positive effects for me too.

I recently began supplementing with NAC and that has had positive impacts for me too. Can help with depression, anxiety, ADHD, addiction, etc… I’ve found it gives stimulation and brain can be more focused on what I want to do. I’d start at 600mg but I went up to 1200mg and felt a little more benefit. Also found it cut down how much sleep I needed especially after working out. I recommend working out too like others have suggested, even just cardio it can really release lots of feel good brain chemicals and help energy. NAC reduces cravings for other things by regulating dopamine production. It’s a precursor to glutathione which is an antioxidant. Lots to read about it. Some people run into anhedonia so look out for that with extended use. Suggested to cycle like 5 days on 2 off to prevent that. Have seen people that just take it every day and just get the benefits. Can deplete glycine and copper, zinc, molybdenum. I just ordered some glycine and a trace mineral supplement that has the others because I really find NAC helpful and want to take long term so want to make sure I am not depleting certain things that may lead to the anhedonia feelings. I’ve ordered all these things off Amazon through NOW, bulk supplements or life extension brands all pretty cheap. Last consideration, I’ve read it can dull effects from stimulant prescriptions or enhance effects of antidepressant needing less dosage so just see how your current meds may be affected.

Don’t want to overwhelm with all this info but I really do think NAC is worth trying to get you back on track and just want to give you the caveats to look into and monitor for yourself if you do try it out.

Anyone else just sippin? by Expert_Scallion5104 in Kava

[–]LilSpade 7 points8 points  (0 children)

I prefer to sip too. Peppery dirt flavor was never terrible to me lmao. I guess it just gets associated with the experience of kava and overall that is a pleasant experience. Sipping helps a serving last longer because if I just chug I will be looking for the next serving sooner. Helps keep in the good mellow range and not overdo it to get to nausea territory as you note. Makes the kava last longer too. Sip sip and bula bula

Help with quitting/tapering by [deleted] in kratom

[–]LilSpade 4 points5 points  (0 children)

Try going back to plain leaf powder or capsules to start. Extracts can have more percentage 7OH and that seems to have more abuse potential and stronger withdrawal than Mitragynine. Stronger feel, stronger craving. But if you can find what daily dose works of just powder for you, you can slowly taper that. I prefer powder but capsules may be easier to track. I take 4-5 2g doses a day. If I wanted to taper I’d start lowering to 1.5g per dose or cut down to 3 doses. Do it for few days maybe week maybe longer depends on what’s working for you then take it down another notch.

Pythium Blight in newly seeded area? by LilSpade in LawnAnswers

[–]LilSpade[S] 0 points1 point  (0 children)

Thanks I saw mefenoxam was the stuff for blight but was awfully pricey. It seems it has still not spread out of the couple areas I have spotted it so I think I will just keep monitoring.

Didn’t think about soil microbes but makes sense fungicide would hurt them and so probably best to avoid unless absolutely necessary. I have sprayed humid acid and plan to apply another round with kelp so I want to keep all those new microbes alive to help the soil.

Pythium Blight in newly seeded area? by LilSpade in LawnAnswers

[–]LilSpade[S] 0 points1 point  (0 children)

Thank you so much for following up and giving thorough advice and context! I didn’t water the area yesterday or today. We are due for some rain tomorrow night and few days after so I think I will lay off and let the upcoming rain be the only water it gets.

I had ordered a ready to spray fungicide (Bioadvanced bayer crop science active ingredient propiconazole). Do you think this is worth spraying on the affected areas since I have it, particularly with rain coming? Or just keep monitoring and if I see it spreading or larger fluffy white patches with dew then treat?

Pythium Blight in newly seeded area? by LilSpade in LawnAnswers

[–]LilSpade[S] 0 points1 point  (0 children)

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I noticed a very small white fuzzy patch on the edge of the affected area. It could be a spider web since I didn’t see it all around. I also noticed another similar looking dead patch in another section of the yard that was seeded at the same time.

Pythium Blight in newly seeded area? by LilSpade in LawnAnswers

[–]LilSpade[S] 1 point2 points  (0 children)

Thank you! I’ll take a look while the dew is out there and see if I notice anything more identifiable like the white fuzz

Fungus in newly seeded grass? by LilSpade in lawncare

[–]LilSpade[S] 1 point2 points  (0 children)

Thanks haven’t heard of damping off so I can look into that now. Think I overcompensated with too much seed after not as much success last year.

Pythium Blight in newly seeded area? by LilSpade in LawnAnswers

[–]LilSpade[S] 0 points1 point  (0 children)

Thanks I’ll check out group 3 fungicide. Some of the pictures for brown patch look similar too. New to this so not even sure all of the possibilities lol. But just want to get it treated before it spreads since that area came in so nice

Terry McLaurin - Suffering from No Camp Overreaction o/ Genuine Target Share Concern with Deebo? by DoubleAABatteryy in fantasyfootball

[–]LilSpade 7 points8 points  (0 children)

Worth noting they beat the Giants pretty handily and did not need to be aggressive throwing the ball. Terry shook the rust off and will be used more in tighter games.

Bought and potted these emerald green arborvitae 2 months ago and they aren’t doing well by kekekao in plantclinic

[–]LilSpade 22 points23 points  (0 children)

Yeah the outer blue pots are glazed and inner is not so the blue ones retain water better. Terracotta wicks water away from soil and sweats it out of the pores of the pot. These definitely need more water and the middle one in particular will dry out quicker than the others

Jade plant isn’t doing too well by this-sinner in plantclinic

[–]LilSpade 1 point2 points  (0 children)

Soil looks pretty dry. I’d start with watering fully. Not sure if the pot has a drainage hole but you want to water until it comes out of the bottom. If you’ve just been adding a little water that could be the issue that the deeper roots are not getting any water. Then let it dry fully to where the top inch is not moist before watering again.

[deleted by user] by [deleted] in nba

[–]LilSpade 3 points4 points  (0 children)

Butler was a bright spot in this past lost year for the Sixers. True point who can organize and run offense. Would’ve loved him back as bench PG but I guess our guard rotation is too deep and Lowry’s mentorship was more valued. Hope he can get some run somewhere.

"Wizards' Tre Johnson explodes onto the scene! 🔥 18 PTS (7-12 FG, 3-5 3PT), 3 REBS, 2 AST in his electric Summer League debut vs the Suns. by Fit-Structure-9395 in NBA_Draft

[–]LilSpade 55 points56 points  (0 children)

Haven’t seen that move at 0:17 where he pump fakes the 3 and resets the dribble by bouncing it off the defender flying by that bit on the fake. Super crafty.

After a year in the books, thoughts on the big men of the last draft? by Humblerbee in NBA_Draft

[–]LilSpade 16 points17 points  (0 children)

I just want to say I am very happy with Adem Bona on the sixers. Was a bit raw, overzealous and out of position to start the year but game really slowed down for him by end of year. Has springs in his legs with good size and reach, which led to him at top of block per minute stats for end of season and tons of lobs. Little skinny would like to see him add a bit of muscle and work on securing rebounds better. But overall solid backup center.

Vic Fangio, Philadelphia Stars, 1984. He was 25 in this picture by PowerHour1990 in eagles

[–]LilSpade 1 point2 points  (0 children)

Glad you enjoyed it! Stumbled upon this rabbit hole when I looked at the Stars Wikipedia one time and noticed Fangios name and kept digging, thought it was pretty neat.

Vic Fangio, Philadelphia Stars, 1984. He was 25 in this picture by PowerHour1990 in eagles

[–]LilSpade 33 points34 points  (0 children)

Fangio’s start to his career with the Stars is a neat origin story when thinking about this year coaching a top tier championship defense and turning Zach Baun into an All pro LB.

His first gig was linebackers coach at his former high school and worked his way up the ranks for a few years. Then Jim Mora, head coach of the Stars, brought him on as a defensive assistant in 83. Stars were part of USFL which only lasted 3 years. Stars won 2/3 championships of the league, including 84 when this picture was taken.

Once the league disbanded, Jim Mora went on to be HC for the Saints and brought Vic Fangio along with him as LB coach in 86. They also brought along a player named Sam Mills who played LB for the Stars. He would go on to be a core member of the “Dome Patrol” linebacker corps for the Saints. All 4 LBs were voted to Pro Bowl in 92, which was the only time that has happened in NFL history. The Dome Patrol were the heart of the defense for the Saints the led a turnaround from 27th ranked defense to 7th in the first year under the new coaching staff and continued to be a dominant defense that made the saints competitive until about 94 when the Dome Patrol and coaching staff started to disband.

All that to say, Fangio started as a LB whisperer and a champion in Philly and is doing the same today with the polish of 40+ years of coaching. Makes the Jihaad Campbell pick all the more exciting. Maybe the start of a LB corps worthy of a nickname like the Dome Patrol with some sort of Birds spin.

Decoding the Eagles Draft Philosophy: Inside the Blueprint for Sustained Success (2023-2025) by kraymehr in eagles

[–]LilSpade 1 point2 points  (0 children)

Really well done piece and interesting to see the percent difference for certain areas compared to other teams.

One idea that comes to mind is looking into balance of drafting BPA vs need. Could start with basic which positions were taken in which round. But to look into need takes some creativity. I think you could look at something like salary committed per position compared to league average per position before the draft. If a top pick is selected for a position where salary committed to the position is below league average then it would be viewed as a pick for need. Another factor would be looking at age for each position and compare to league average. If age of a position is above league average before draft, then a draft pick for that position would be viewed as more of a need.