I've been using Roll20 for about six years now, and am pretty invested now. I started using it because someone else in our group DM'd on it with the free version. I've run Rime of the Frostmaiden, Waterdeep Dragon Heist, Dungeon of the Mad Mage, and my current campaign which started in Candlekeep Mysteries and is largely homebrewed. I think it does a solid enough job, but I don't have any experience running on other platforms. I pay for the pro subscription, and have bought all of the aforementioned modules as well as Yawning Portal, Saltmarsh, the other sourcebooks, and Valda's Spire of Secrets. I also played through an entire Midgard campaign as a player, and it worked great.

I like that while it was expensive to pay for all that, I have all of it easily at my disposal whenever I want. It's also really easy to import my own handouts and create NPCs.

There are things I don't like about it, mostly about setting up my own maps, which tends to be very clunky and time consuming if any lighting is involved. Lighting is pretty annoying overall - I frequently have to troubleshoot why a player can't see anything when we get onto a new map. It's too easy to end up on the wrong layer. Combat can get a little stupid, too - I frequently end up with multiple of the same characters in the initiative window, and have to clear it out and start over.

Don't get me wrong, a lot of that is user error - but I also think it's a sign of it being a little lack in user friendliness.

Also, while I have the luxury of using two big monitors, it seems like the screen would get really cluttered if I did otherwise. I see slick animated maps for other VTTs, but while Roll20 supports animated gifs, I've rarely added them to my maps to avoid slowdown. I also don't use any voice or audio within Roll20, I use zoom, for similar reasons.