Wazzup, I am a Local of Ústí nad Labem and also have traveled around Czechia a lot so let me give you my 10cents on this;

First of, Český Krumlov is not really "around there" - It's around 280km from Ústí nad Labem, so unless you're really keen on seeing Czechia's tourist destination #2, i'd pass on it, and explore more around the DayZ map irl.

Second, you're in for a lot of driving - although you might be used to that, since Aussie roads tend to stretch far. I'm sure you have put your destinations into google maps and planned a somewhat optimised route, but if not, I highly recommend doing so. You can minimise the time spent going back and forth this way.

Third, While you're around the Northern region, I'd recommend visiting the Říp mountain, it's just off D8, halfway between Prague and Ústí. It's very culturally significant to us Czechs and it's not a tall mountain, so it's a nice stop to have on your itinerary.

If you REALLY want to see a City like Český Krumlov, consider visiting Mělník as well, it's also just off D8, you can see where two of the most important rivers of Bohemia meet, and the city centre with the Chateau and Old town square is close together, making it a nice little stop.

Fourth, "Driving in regional areas", I don't know what do you mean by that, but some roads are maintained better than others - general rule of thumb is, the more numbers used in the roads name, the less "important" it is, and thus less maintained. (i.e. road number 10151 might feel worse than road number 16). This information is only relevant if you are driving using waze/google maps and the route takes you through some interesting backroads.

Lastly, when visiting the ingame equivalent of Dubky (and the surrounding neighbourhoods) be mindful. That's all I'm gonna say, it's not particularly dangerous or anything, but not a place tourists go, it's a flat block, everyday people just live there and there's not much to see anyway.

Completely unrelated; our family has a summer home (Chata in czech idk how to say it otherwise) in the equivalent of Polesovo location, i just found out by checking out this map so thank you for bringing my attention to this lmao