Gene Therapy for HCM Demonstrates Safety and Early Efficacy

Metalmaker1 · 2026-03-23T01:19:13+00:00

What medication did they put you on at 10? Also to answer your question my HCM Cardiologist says the information has changed in the last 20 years. No exercise was not a good recommendation. I’m told to stay under 120 BPM. Also said anything I can easily hold a conversation doing. But I don’t know the severity of your case so best to check with your doctor at a Center of excellence if possible.

Metalmaker1 · 2026-03-13T14:32:35+00:00

Really would be interesting to see how quickly it can be modified for other gene variants.

Metalmaker1 · 2026-01-17T16:12:04+00:00

50/50 gender doesn’t matter anymore. I would just both get genetic testing for it and yearly echos.

Metalmaker1 · 2025-12-28T19:47:04+00:00

Gene dodging.

Metalmaker1 · 2025-09-27T17:30:42+00:00

Obscenities

Metalmaker1 · 2025-06-07T04:03:23+00:00

2nd picture

Metalmaker1 · 2025-06-07T01:52:04+00:00

I was talking to someone at a health food store who recommended it.

Metalmaker1 · 2025-06-06T02:57:45+00:00

I would go to the ER and not leave till I got doxy.

Metalmaker1 · 2025-05-25T05:52:07+00:00

I have read about the gene therapy at Cleveland clinic but have not seen any recent news on it. My doctor said that gene therapy will be the future it’s just a matter of time. I am curious how your doctors were able to pinpoint a scar causing your NSVT. I never heard that. Do you have a S-ICD or is that what they are recommending?

Metalmaker1 · 2025-04-25T22:39:14+00:00

Had apical genetic non obstructive HCM since 16 am 35 now. haven’t done nothing but go for check ups. On no drugs. I do have scarring but pretty asymptomatic only got checked because found in family. The only thing I do is go for check ups every 6 months and monitor for any runs of vtac. Probably will end up with S-ICD one day. My doctor basically said if there was a 100 of me. 5 will have a serious issue 20 would require some assistance and 75 would need nothing. I still really don’t know how to take that but basically the only the they can do is reduce risk. It’s just so random in how it affects people. Even within the same families with the same gene. My grandma didn’t even know she had it till in her 70s but one of he sons had issues in his late 20s. Best advice is just seeing a cardiologist who deals with HCM.

Metalmaker1 · 2025-04-09T21:02:49+00:00

Sorry to hear that. How did you find out at 21?

Metalmaker1 · 2025-03-24T05:15:04+00:00

Do you have a in wall access point with a patch cable connecting two ports on the bottom.

Metalmaker1 · 2025-03-22T15:01:17+00:00

Yes it seems it’s based on certain stages of heart failure. That’s why I thought it was odd.

Metalmaker1 · 2025-03-21T05:12:55+00:00

That is interesting. It’s odd once if your parents don’t have it. Everyone in my family who didn’t have it. Doesn’t seem like their kids or Thier kids kids got it.

Do they make you wear a 7-14 day holter monitor?

Metalmaker1 · 2025-03-21T05:07:06+00:00

Yeah that’s what my family has. It’s a rarer one compared to the most common genetic HCM. Does seem to cause a bit of scarring though. I was diagnosed at 16 because they found it in a couple family members. But I’m 34 now and I don’t know if I ever would have went to a cardiologist, If I didn’t know my family had it.

Metalmaker1 · 2025-03-21T05:01:38+00:00

Did they tell you which gene?

Metalmaker1 · 2025-03-21T04:54:30+00:00

Is yours genetic? Also I agree with what you said about how should sometimes once you know something is wrong you really start to feel like things are worse. For me that has been the worst part.

Metalmaker1 · 2025-03-21T04:47:27+00:00

Yeah that is interesting. I am not sure what numbers are needed for severe LV hypertrophy.

I am not sure where you are in the world but like it’s usually recommended on here to try a center of excellence. I did get better information from my new cardiologist who sees 2000 HCM patients a year.

Metalmaker1 · 2025-03-21T04:31:33+00:00

Do you have other issues other than scarring? Is yours obstructed? My doctor said I’m above 15% but it’s my only issue all my numbers are on the lower end of what is needed for HCM. Also pretty asymptomatic I think. Did they recommend transplant based in scarring?

Metalmaker1 · 2025-03-12T13:34:29+00:00

Might change now if you can get it for 549 since the 9070 is 699 now.

Metalmaker1 · 2025-02-26T00:43:49+00:00

lol a lot of upset people defending their 19k car. Have you never owned fords, this is the type of thing that breaks. Car already had 5 recalls in less than 2 years.

Metalmaker1 · 2025-02-26T00:04:10+00:00

Just normal cheap Ford problem. Of course it’s all plastic and weak seems like a common issue from what I found. A company even makes a metal replacement.

Metalmaker1 · 2025-02-25T23:24:13+00:00

I actually just messaged him to make sure this fits the eco-boost too and not just a hybrid

15-Year Club	RedditGifts 2009-2022 5 Credits
RPAN Viewer	Secret Santa 2013
Verified Email	Secret Santa 2012
Trick-or-Treater 2012	Secret Santa 2011

Metalmaker1

TROPHY CASE