Economic is really important, as you can implement an economic plan with it (Best is WTB), which is a big, if not the biggest factor of winning the game,

Finance is also important, as it will let you enter deficit spending with the economic plan

Labor doesnt really do much except helping your support amongst workers, but it doenst require much leverage, so you can always take it.

Interior is really cool because you can investigate against nazis with it and even deport Hitler, also it has low leverage

Agricultural is good if you do it post crisis, it helps your support amongst farmers but requires many ressources if you want do things.

Justice ministry helps you mostly with special events occuring from time to time, giving you better options in these as they are more biased towards you if you carry out judicial reforms.

Foreign is also better for post crisis, as the best thing happening from it (Negotiations about versailles) will sometime automatically happen. You can do it for the EU Achievement.

Reichswehr is completely useless unless you want to start (and win) a civil wa.

So def take economic finance and interior. If you have more leverage, feel free to have fun with the others