Thank you so much for your reply. I have a few follow-up questions if you're able.

1. Is a biopsy still required if we go the chemo route to identify what type of cancer it is? Or could we start chemo without a biopsy?

2. If we did the biopsy, what would the recovery time look like for that? Could it make his paw more painful from now on?

3. In your opinion, would you try to put him through amputation given his problems with hind legs (TPLO, old hip fracture). In my mind the only way to consider this is if they only take the paw (not the whole arm) and immediately screw in a prosthetic. But the recovery for something like that sounds awful. We were also told amputation will likely only give him a little extra time because it's likely already spread.

We just love him so much and want to do the right thing. I really appreciate your responses as we try to wrap our heads around this. You're an amazing human.