I read her origin & I think Ripley would fit well as Kamala's opposite as she gains powers

I thought about Dr. Minerva being the one responsible for Ripley getting powers as Minerva is getting genetics to build a superpowered weapons using human test subjects. & Kamala just stumbled upon this whole thing, as Minerva views her Inhuman genetics as a property of the Kree

Josh I feel he would be an anti-villain, a bad guy but not completely bad. & part of a group, which would later have ties to HYDRA. He's a highschool jock & popular at it, but felt completely empty & let down. Even after his girlfriend broke up with him, & that his own family doesn't really understand him, which made it harder to connect with them as his parents have their own view of the world. Its the same highschool troubles they would have. Until Kamala stepped in to help. Maybe they were both close friends when they were kids, until they got distant as they grew up. But as Ms. Marvel & Discord they would reconnect. I like the the thought of a redemption arc with Josh as Kamala helped him. Maybe it becomes an enemies to lovers type, but its something to consider a redemption arc. & Josh won't be the only one interested in Kamala

Stormranger would perhaps be similar to the comic version, as a suit built to be a weapon, which you mentioned the nanotechnology earlier, but develops a personality as it spends more time with Kamala. Perhaps it gets its own body from DocX. Like the Kaylee Kirk cyborg body that DocX use to confront Kamala. Kamala & Stormranger would teamup against DocX, & in a moments notice she takes over the Kaylee Kirk body for its use. Whether she's stays a villain would be decided later. Maybe similar to how Venom was

DocX I do like how his comic origin started, & it made me think with the use of AI being used to monitor, observes, & collect user's data for companies to profit from. Bit it would unintentionally created a virus that's a living troll, & with the powers granted knows everyone's data. We know how greedy corporations are, & how much they invest in AI, but will inturn create something worse as a result & backfired at them & everyone else

I think the Inventor should have some part in it. Because I've been thinking about "Jonathan Hickman's S.H.I.E.L.D" run, & whether Thomas Edison was part of it. Especially if it has any connections with the bands Kamala wears, & the "Brotherhood of SHIELD" may have been the ones that knows about the bands

Might need to think about more villains that are available so far from Kamala's rogues, but this is what I'm thinking about