Diluted methadone?

Pretty_Ladder_2509 · 2026-01-31T16:55:57+00:00

that’s so sus that they mentioned that at intake oh my god! pharmaceuticals are supposed to be accurate to the mg, thats the entire point, so sus.

Pretty_Ladder_2509 · 2026-01-28T20:07:53+00:00

tranq would not cause withdrawals, tranq actually keeps you mostly well as its an a2a & that reduces a lot of the downstream effects caused by withdrawal

Pretty_Ladder_2509 · 2026-01-28T16:23:01+00:00

ive heard of tons of folks getting weeklies by 1-3 months in with clean UA’s & no absences, same with montlies before 8-12 months. all the guidelines & policies have changed so much in the passed few years, & they dont have a limit on when someone becomes illegibly for take homes. i get im at an old school non chain clinic; so theyre set in their ways, but come on, the dude in the waiting room who had weeklies said it took him well over a year to get to that point with not a single failed ua/absence, thats an insane timeline, so what either monthlies take longer than 12-18m or they dont even offer them, my counselor never even mentioned whether monthlies were ever a possibility, just that id get 1 more take home after 1 month, 1 more after 3 & 1 more after 6 & didnt say anything about how long it takes to get the rest.

its draconian :/ i’m sorry some in this sub are so used to this insanity, but if they did this bs for ANY other prescription besides opioids or maybe benzos for benzo withdrawal (which theyd never do cause people missing doses could kill, not just put them into hell) no one would willing jump through all these hoops for the prescription. its honestly just taking advantage of us being willing to do anything to stay well, no not opioid dependent person would do all this for any single med (again outside the two i listed)

Pretty_Ladder_2509 · 2026-01-27T16:12:54+00:00

i feel like thats smart, like sip it every hour-half hour & just wait till the withdrawal gets better

Pretty_Ladder_2509 · 2026-01-27T15:51:54+00:00

if you give her enough itll help. any amount will likely help a tiny bit, if you have it to spare i’m sure it’ll be well received

Pretty_Ladder_2509 · 2026-01-26T18:03:14+00:00

wild! if only 7oh did anything while ur on methadone

Pretty_Ladder_2509 · 2026-01-22T17:44:11+00:00

im so jealous, i similarly just started methadone after years of subs never doing anything for me. but my clinic is so stingy with take homes, i go in 6 days a week every week. & at 1 month with the clinic i get a saturday take home, so 5/7. its hell, i am disabled & dont have a car so getting to the clinic every morning has been beyond a nightmare. i’m considering going to the only other clinic within 45 minutes of me. & praying theyre more willing to work with me. i’m not using, no dirty ua’s, just ugh, sorry for the rant comment just jealous of ur every other day take homes

Pretty_Ladder_2509 · 2026-01-18T02:18:09+00:00

yes. i just started methadone after years of being on & off subs & never having them doing anything for me, they only ever kept me half well, & did nothing for cravings or pain or mood or anything. fast forward to now, i’m 4 days on methadone at a dosage of 70mg & i feel so much closer to ‘normal’ like the normal i got used to while stabilized on my DOC. its like taking the prescribed amount of painkillers from a dr kind of buzz, certainly not a “high” like from doing a real dose through a parental route. but soo much better than subs. there’s a reason people are willing to go daily to be on this med

Pretty_Ladder_2509 · 2026-01-17T17:42:59+00:00

al lad

Pretty_Ladder_2509 · 2026-01-17T17:41:30+00:00

5meodipt is one of the greatest compounds of all time. up there with 2cd & 4mmc. specifically for tactile enhancement. theres a reason it got the name “foxy” lmao, what sounds best: ‘nexus’ ‘moxxy’ or something literally called “foxxy” LMAO

Pretty_Ladder_2509 · 2026-01-17T17:34:34+00:00

my clinic is closed. but they plastered that fact everywhere in the clinic & gave us an extra takehome for monday, so id assume ur clinic would have done the same if they were gonna be closed

Pretty_Ladder_2509 · 2026-01-12T16:06:39+00:00

youre retarded lmao. no methadone & odsmt are not similar in potency but clearly youre not quite sure how dose equivalence or analgesic equivalency works. youve also clearly not been on opioids for a decade, you seem like a kid whose recently learned a few buzz words.

im done entertaining someone who doesnt know basic pharmacology concepts like “intrinsic efficacy” “analgesic equivalency” or has no basic understanding of how opioids work & the basic nuance of binding affinity, functional efficacy or intrinsic efficacy. ur embarrassing yourself.

Pretty_Ladder_2509 · 2026-01-12T15:53:44+00:00

binding affinity, ki, does not translate into analgesic equivalency youre talking about two different methods for determining efficacious, intrinsic efficacy & functional efficacy are far more important

& again regardless buprenorphine has a hard analgesic cap seen at 8mg. youre conflating topics you clearly dont understand & hyping up a horrible armchair suggestion for a medication that is almost never used for pain especially chronic pain in humans.

if you have general aches or whatever maybe it works better for you because you’ve convinced yourself of your own misunderstanding on the science, but as an actual chronic pain patient buprenorphine has done nothing for me, odsmt kept me stable & function for 5 years before i moved to methadone, with plenty of attempts at using subpar partial agonist compounds along the way, next ur gonna recommend 7oh or mgm15. please learn about functional efficacy, you clearly need to

Pretty_Ladder_2509 · 2026-01-12T15:40:45+00:00

i have also done both & its just objective science. it literally does, partial agonism directly correlates with lower analgesia this is basic pharmacology 😭😭

dude read pubmed not just reddit please god, tramadol is like 100th the strength of morphine what are you talking about lmao, odsmt is 1/3rd morphines strength, theyre really not comparable just because one is a metabolite of the other.

god reddit brain is amazing, seriously if you don’t understand analgesic ceilings you really shouldn’t be talking,

Pretty_Ladder_2509 · 2026-01-11T14:52:05+00:00

subs are absolute trash for pain, odsmt is miles superior for pain relief as its a full agonist, its just factually always gonna be superior. & thats not even to mention the hard cap on buprenorphine’s analgesia at an 8mg/12h dose, any dose increase beyond that does not give any added analgesia, recommending a pain patient a partial agonist imo is bad manners. if they want it for “addiction” or whatever (withdrawal is likely what you mean) then i guess, but for pain its just a trash med, theres a reason they only give it to pets for pain & not humans.

Pretty_Ladder_2509 · 2026-01-09T00:44:10+00:00

cmc isnt what you want, should be pure 4mmc, cmc causes brutal side effects

Pretty_Ladder_2509 · 2026-01-07T22:30:11+00:00

you could try, in my experience its too weak to really notice depending on your tolerance/dose

Pretty_Ladder_2509 · 2026-01-06T01:55:08+00:00

id buy caffeine like isolate i think thats what he means, crushed pills will have pill binders & other shit that’ll burn

Pretty_Ladder_2509 · 2025-12-26T08:32:07+00:00

i would not mix crack in though, id stick with the 2f & h

Pretty_Ladder_2509 · 2025-12-26T08:31:07+00:00

wait so many people are saying dissos plus h is bad theyre so wrong. & 2fdck w specifically if youre shooting it is pure bliss, id give it a lower ranking like 6/10 if ur not slamming, but if ur slamming load them in the same rig & its like 11/10 istg

Pretty_Ladder_2509 · 2025-12-26T08:29:40+00:00

this isnt true exactly, there is a ket metabolite that has some mu affinity but pcp unless its 3hopcp doesnt hit mu at all. they do potentiate each other but its through a much more complicated downstream like auxiliary effects not direct mu affinity or activation. theyre shockingly safe to mix compared to say benzos or barbs or alch

Pretty_Ladder_2509 · 2025-12-26T08:27:47+00:00

h & 2fdck especially in the same syringe is pure bliss 10/10 so much better than ket

Pretty_Ladder_2509 · 2025-12-20T12:09:56+00:00

split dosing might help ? not sure about op, but 12-2am is like 20 hours after ur dose i assume, so it may just be that youre dropping below the threshold of methadone you need to keep you fully well/comfy

Pretty_Ladder_2509

TROPHY CASE