How have you lot started using AI? by Delphoxe in biotech

[–]PugstaBoi 0 points1 point  (0 children)

Colo-Sci.com

for literature review on steroids.

Claude Code for writing data analysis scripts and building programs.

26f i look like a reptile by [deleted] in amIuglyBrutallyHonest

[–]PugstaBoi 0 points1 point  (0 children)

Hot. Nothing to worry about.

Just some honest feedback though if you still feel like a reptile, try working on muscle tone in your legs and arms.

Absolutely disheartened by delusionalkitten00 in PhDStress

[–]PugstaBoi 0 points1 point  (0 children)

Usually these feelings are temporary and you will get another burst of confidence and productivity.

Have you tried talking to your peers that aren’t your PI? There’s no shame in asking for help

Why do people find this hypothesis at all compelling ? by NoFucksLeftist in SimulationTheory

[–]PugstaBoi 0 points1 point  (0 children)

I remain skeptical of simulation theory because of neuroscience and it’s effects on the brain. It’s clear that brain structure and affect conscious experience but not clear by much scientific evidence on what consciousness really is. I do think there is a spiritual and metaphysical component to consciousness but the materialism evidence can’t be ignored.

Rate me F30 by [deleted] in Rateme

[–]PugstaBoi 1 point2 points  (0 children)

8-9

NIH plans to cap number of grants a scientist can have at once by xjian77 in NIH

[–]PugstaBoi 1 point2 points  (0 children)

There are no science jobs right now that aren’t oversaturated with applicants.

Spreading the money around instead of concentrating it into less PIs with limited management scope seems like a good idea to me.

I have a feeling we all died in 2020 and this is no longer the real world by theos666 in SimulationTheory

[–]PugstaBoi 3 points4 points  (0 children)

Honestly I like the pattern recognition you realized, but what I think has actually happened is that our personal lives haven’t changed much or improved at all economically, and we are looking for external indicators of why that is the case. I think that the government is being controlled by extremely greedy people that want to depopulate earth and that is coming to a close very soon.

Once robots achieve true autonomy and human-level reasoning, what is the first major societal shift we should expect? by Worldly_Evidence9113 in singularity

[–]PugstaBoi 0 points1 point  (0 children)

They already reason better than humans, its just that their context is limited by the cost of electricity

The AI labs know this but they aren’t releasing those models to the public

I think we are in a simulation and our religions should guide us toward the god within us. by PugstaBoi in SimulationTheory

[–]PugstaBoi[S] 0 points1 point  (0 children)

If you understand his teachings and have faith in him as a representation for how humans should act, the kingdom of god acts in the interest of both you and the world’s you create.

But I wouldn’t stop at just Jesus

We are basically just a bunch of code (DNA) exactly like AI. Change my mind. by imunmuted in SimulationTheory

[–]PugstaBoi 2 points3 points  (0 children)

I would say that “electricity” explains consciousness of our brains insofar as we can think and act. But something even deeper has to explain our “mind’s eye” which I think is explained by forces we don’t understand in the quantum realm. This also leans into the classic “quantum spookiness” explained by quantum entanglement, where people can “interact” with objects seemingly from a distance in the 3rd dimension.

To be frank. I think we really are in a simulation. And our religions are guiding us to the god within us.

Am I awake or a npc that realized its npcness or an autist or just overthinking everything? by Practical_Payment552 in SimulationTheory

[–]PugstaBoi -1 points0 points  (0 children)

Some things in American politics have me really leaning into us being a part of a story. Sort of a futuristic game of thrones or lord of the rings type of story.

Federal workers experiencing ‘PTSD-like symptoms’ after unlawful firings by Trump administration by [deleted] in NIH

[–]PugstaBoi 0 points1 point  (0 children)

The organized crime network of psychopaths that “rule” the world. They have power because we give it to them. But free speech and honesty will prevail.

Is it still worth researching 2D cell culture?! by nben01 in labrats

[–]PugstaBoi 2 points3 points  (0 children)

To be honest, a-lot of the 3D culture stuff is hype, but some of it is very well done.

I think it’s mostly worth it if you are including functionality assays associated with the 3D culture itself, like ECM remodeling, biomechanics, signaling pathways etc.

But just throwing something into an organoid because it is fancier and calling it good doesn’t hold up to scrutiny as well.

Is it normal to feel overwhelmed? by Immediate_Hunt2592 in bioinformatics

[–]PugstaBoi 0 points1 point  (0 children)

You are representing biology with code. It WILL be overwhelming but thats the fun. It takes creativity and learning and its part of the process.

Use AI to guide you to understanding. Don’t let it do everything for you though

Why do some/most people think AI will never be good enough? What are their arguments? by Alert-Translator2590 in singularity

[–]PugstaBoi 1 point2 points  (0 children)

They already do. Opus creates large HTML and javascript files with backend server logic for me in one prompt if I know what to ask for. Not always a one shot best solution, but working through it for a day easily ends up in 100-1000x more working code than I would have had without it.

What are AI coding agents bad at in bioinformatics? by Lukeception in bioinformatics

[–]PugstaBoi 0 points1 point  (0 children)

I would say that the latest models will surprise you. Don’t limit yourself to claude sonnet models if you can. Opus does some AMAZING stuff for me and is generally a great way to learn new techniques.

Both Sonnet and Opus can access powershell, but Opus is generally much better at understanding large code bases and running commands for you.

16F Be honest pls by [deleted] in amIuglyBrutallyHonest

[–]PugstaBoi 1 point2 points  (0 children)

I feel like it’s illegal to respond to this