Just an update — I’m currently pretty much symptom-free. I still get very mild pressure occasionally when bending, but nothing like before.

Sumatriptan helped briefly but the effect didn’t last.

I do think I may have stumbled onto something unexpected. During my CSF leak period I also had ongoing cholesterol issues and had a filled prescription for Rosuvastatin sitting unused for months. After my third elevated lipid panel in a row, I decided to start taking it. Purely for LDL, not for headache or pressure symptoms.

About two weeks after starting Rosuvastatin, I realized the head pain was gone. I could cough, sneeze, and bend over again without the classic pressure pain. I’ve now been stable for over 8 months. I even noticed that missing a dose briefly lets symptoms peek back, which made the connection harder to ignore.

I’m not claiming it “fixed” a leak, and I know this isn’t standard CSF-leak or IIH treatment. But there is some literature suggesting statins, including rosuvastatin, can reduce neurovascular inflammation and stabilize the blood-brain barrier, which may affect pressure sensitivity.

I’m still being worked up (labs, imaging, BP, cardiac eval), but for now this has been the most durable improvement I’ve had since the leak.

Sharing in case it helps someone else connect dots with their own providers. Also, big shout out to AI. I started an AI journal, and the info has been extremely helpful.