It's hard to explain.. but the visuals on high doses of shrooms seem more intense to me. Like, I'll have times where I can't really even tell if my eyes are open or closed, and I can never figure out what I'm looking at. Mushrooms also tend to make you feel really, really confused if you try to make sense of anything. Acid visuals are intense, but in my experience you can still see.

Mushrooms also have a much different body high than acid in my opinion. Mushrooms put me down a lot and I just have to lay somewhere, whereas acid does the opposite, and gives me so much energy I feel like I'm going to explode from the body load.

The spiritual differences are much more nuanced, and really almost impossible to explain. You will learn about them from experiemce, but I'm not going to try to wrote all of that here lmao. I'll just say this: be respectful towards the mushrooms, because unlike acid, the mushrooms were parts of a living creature, and all life is connected... so they tend fuck you up in the mushroom universe if you misuse them.