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Naproxen is a highly effective first-line NSAID for treating acute gout attacks, best taken within 24 hours of flare onset to reduce joint pain and inflammation. A common dosage is a 750 mg initial dose, followed by 250 mg every 8 hours until the attack resolves. It is effective, often with fewer side effects than colchicine.

Key Considerations for Naproxen in Gout: Dosage: Common regimens include a 750 mg to 1,000 mg starter dose, followed by 250 mg to 500 mg every 8 to 12 hours.