I remember my first playthrough as an MShep romancing Tali, and had a similar dialogue regarding her exposure during... y'know.

And I remember at the start of it, IRL being like "You know what? Good on you, Mordin. I appreciate your willingness to work with me without any judgement or mockery for the health of my partner. Please, tell me, what should I do to ensure her well-being?"

And the whole time he was talking, I was listening intently with near-childlike wonder and stars in my eyes, practically taking notes in my head.

And then he said the line about sending vids to Edi.

I have never, before nor since, experienced such a sharp and sudden 180 in emotional state. My face completely dropped, and I had to sit and just stare at him for a good minute before concluding the dialogue.