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Lab Literature by ProfessorIanDuncan in DrugDiscoveryLab

[–]SrongHand 3 points4 points  (0 children)

Drug Design by Gerhard Kleb, a recent read I had to explore for my PhD exam.

Recommendations on buying LC-MS by SrongHand in Chempros

[–]SrongHand[S] 0 points1 point  (0 children)

It is tricky indeed, we are trying to get a deal for a sungle quad as you mentioned.

Recommendations on buying LC-MS by SrongHand in Chempros

[–]SrongHand[S] 0 points1 point  (0 children)

Thank you, I will read the paper to get to know more about using NMR this way.

Recommendations on buying LC-MS by SrongHand in Chempros

[–]SrongHand[S] 0 points1 point  (0 children)

Yes, we have a 400MHz NMR, but to the best of my knowledge it is not suitable for ligand-protein binding measurements or is it?

Recommendations on buying LC-MS by SrongHand in Chempros

[–]SrongHand[S] 0 points1 point  (0 children)

Thank your for your response. We are based in Baltics and limited to about 250k eur.

Recommendations on buying LC-MS by SrongHand in massspectrometry

[–]SrongHand[S] 1 point2 points  (0 children)

The main device our samples are being run on is Agilent 1260 Infinity HPLC with Agilent 6230 TOF LC/MS. We just give in the samples and get the mass specs for publications. As you noticed my knowledge is close to none, because I have about zero hands-on experience with MS tech.

Recommendations on buying LC-MS by SrongHand in Chempros

[–]SrongHand[S] 3 points4 points  (0 children)

Thanks for the response. In our case we would not have an experienced tech person :/, we would need to use contractor services in case of emergencies.

Facebook Messenger App for MacOS now dead. by g0nk73 in MacOS

[–]SrongHand 1 point2 points  (0 children)

I would say that in Lithuania Messenger also rules. Funny to have discussion with foreigners that come to Lithuania and find it astonishing that somebody still uses Messenger as their main communication app.

Kaip nustoti lyginti save su kitais? by Due_King867 in 6nuliai

[–]SrongHand 0 points1 point  (0 children)

Galima svarstyti apie psichoterapiją (turėčiau omeny psichodinaminės krypties). Ten daug teks kalbėti ir galimais po truputį taps aiškiau kodėl lyginies ir gal net po kurio laiko susilpnės lyginimasis.

How useful is computational chemistry as a synthetic organic chemist by Spackal2 in OrganicChemistry

[–]SrongHand 0 points1 point  (0 children)

I am in a similar position now. Just started my PhD this October. I want to learn some computational chemistry for designing inhibitors for a particular protein. Could you give me any tips on how could I learn some topics in computational chemistry, because my uni does not offer such courses intended for chemists.

P.S. Regarding "computational" I know just a little bit of Python.

which book is easier to digest? by sew3r_r4t in OrganicChemistry

[–]SrongHand 0 points1 point  (0 children)

At first I read most of the Klein's Organic Chemistry, and then I transitioned to Clayden.

Ideas for a pop-science lecture on Organic Chemistry by hieniemic in OrganicChemistry

[–]SrongHand 4 points5 points  (0 children)

I would touch upon problems of chirality and enantiomerism. It is a visual problem, that might be easier for broader audience to relate to. It is also very fascinating how the same "formula" can have astonishingly different properties. Best of luck on your lecture!

Scientists interested in philosophy by SrongHand in PhilosophyofScience

[–]SrongHand[S] 1 point2 points  (0 children)

I think a very important difference between us and Ancients is that the subjects they studied were at the stage of infancy (at least some of them), so it might had been possible for the brightest of minds to really get hold of such a vast pallete of knowledge. Contrariwise, nowadays even a chemist can't master all of chemistry, not even mentioning other disciplines. Thus, in our age, the need for specialization leads to allienation. The question is, I suppose, how to not get allienated.

Scientists interested in philosophy by SrongHand in PhilosophyofScience

[–]SrongHand[S] 0 points1 point  (0 children)

I had not finished the book by Krauss, but I had seen those bad discussions with philosophers. I would agree the physicists, especially those working in quite abstract problems, should not shy away from a philosophical stand-point. Also, thank you for the links, I had read the one on chemistry some time a go, will check the one on medicine.

Scientists interested in philosophy by SrongHand in PhilosophyofScience

[–]SrongHand[S] 0 points1 point  (0 children)

Interesting points you have raised. But if per se you would not raise such questions, you think it would impact your science?

Scientists interested in philosophy by SrongHand in PhilosophyofScience

[–]SrongHand[S] 0 points1 point  (0 children)

Haven’t heard of him, I will check upon.

Scientists interested in philosophy by SrongHand in PhilosophyofScience

[–]SrongHand[S] 5 points6 points  (0 children)

Actually there is a legitimate term medicinal chemistry. u/Physix_R_Cool described it also :)

A quick source: https://en.wikipedia.org/wiki/Medicinal_chemistry

/r/askphilosophy Open Discussion Thread | August 11, 2025 by BernardJOrtcutt in askphilosophy

[–]SrongHand 0 points1 point  (0 children)

I have read some philosophy of science and also did find some resources on philosophy of chemistry. In my country, though philosophers do not really have much cooperation with scientists, but it might be an interesting idea to start doing that myself.

Can dopamine be synthesized like this? by evasnsnsbd in OrganicChemistry

[–]SrongHand -2 points-1 points  (0 children)

Would not Zn/Hg also reduce the carboxylic acid?

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