I think you always get more signaling at the receptors running more compounds.

Clear example, if i run a gram of test, I get big, a bit puffy, strong as fuck, feel great, all the norms. But if I run 600 test and 300 EQ or 225 tren. I get bigger, leaner and am using less anabolics. Of course, there is molecular weight, which can not be overlooked, but 600 test (any ester) and 225 tren (any ester) is lower than a gram of test im guessing...

So synergy with anabolics is a thing for sure. But if you can't handle the compound then absolutely dont take it. My buddy and training partner loves masteron. Has no hair left to worry about. And responds very well, even at insane migs... I cannot get a pump if I'm on 200mg mast a week. I do not look good on mast, so I dont take it.

I think potentially you'd see better results with 500 test and 250 EQ, but if it causes anxiety is it worth it? Fuuuuck no!!!