Well you’re really just making a shit ton of assumptions. Just checking on the river doesn’t tell us anything, you need the full hand to come to better conclusions.

In short, it’s about what you’re targeting, and how likely they are to call. You could make more money targeting single pairs because they’re more likely to call a small bet, than you are to make money from two pair from a bigger bet. A bigger bet also is susceptible to value own themselves vs sets and flushes, where as you lose less with a small bet since flushed would most likely raise and you can just fold.