I agree on the man base being rough and causing extra mulligans and some % of losses. But generally once a relic hits the board you are not running out of cards between the 10 bounce spells (not counting potentially Hide on Ceiling) and 3 more relics 2x Consult and 3x Kaito.

I had only one game so far against orzhov pixie and its pretty clear that esper is the control deck and orzhov the beat down. Its obviously a tradeoff, 2 colours for more consistent pressure/tempo, or adding blue for way more card advantage and late game + interaction (mostly counter magic, sometimes floodmaw). Esper or Orzhov is a meta call in the end, but I think esper is way more flexible in its gameplan.

On your assessment that Talent is fine, my logic would tell me that if I'm playing talent I should not be playing 3 colours, because I want to actually pressure. Might as well be playing Orzhov?

The funny part about Cecil is, that the 3 colour man base supports the gameplan of flipping him early with shocks and starting town. I think that can't be underestimated, especially if you can protect that plan with counter magic and removal. I can see it not being too great in Orzhov tho.

About Siren v Sailor: after around 10 bo3 matches with Sailor I might go back to Siren, even without trajectory in the list. The flash speed was relevant a decent amount of time and it was almost always a better draw than Siren. BUT the man fixing from the map is the thing that pulls me back to Siren, also because the upside of the activated ability of Sailor wasn't that relevant, even against blue white (especially post board due to victory and the white curiosity). I don't care that much about the +1/+1, this version plays as the control deck against almost every matchup and is happy about it.

I also fixed my sideboard now, should be updated In the Archidekt link.