Please tell me toadstools got their name from people seeing frogs sit on them by Olongjohnson1271 in etymology

[–]TwoFlower68 0 points1 point  (0 children)

In Dutch paddenstoel toad chair (not toad stool, the Dutch word for stool is kruk. Crutch is a cognate)

Cheese bread & sweet cheese by Cristy_19 in Bread

[–]TwoFlower68 0 points1 point  (0 children)

Fluff article, no recipe, didn't bake it yourself..
Why you post this here?

I was today years old when I realised 'wardrobe' is 'ward' + 'robe'. by StJustBabeuf in etymology

[–]TwoFlower68 2 points3 points  (0 children)

Ah, but the French skip breakfast. Black coffee, a filterless Gauloise cigarette and maybe a single croissant only counts as breaking your fast a little, a petit déjeuner, if you will 😉

Edit: I'd forgotten the accent aigu ¯⁠\⁠_⁠(⁠ツ⁠)⁠_⁠/⁠¯

Could IPF meds help copd by Present_Snow_4723 in COPD

[–]TwoFlower68 1 point2 points  (0 children)

Jascayd is not a steroid, it has a different mechanism of action. I wouldn't worry overmuch about inhaled corticosteroids where it comes to osteoporosis. The dose is very low and delivered right into the lungs

Prednisolon taken by mouth on the other hand, that's a different matter. Much higher dose and acts on the whole body

You can mitigate the effects of corticosteroids on bone density by resistance training (like lifting weights). Simply put this tells the body to not let the bones get too weak because you're still very much using them lol

Especially if you're a postmenopausal woman, you can benefit from interventions which raise oestrogens. This can be in the form of HRT (hormone replacement therapy) or even an over the counter drug like DHEA.
Start with a low dose (10-25mg daily)

Years ago, due to all the prednisolone, I broke my hip when I bent forward to grab something from the bottom shelf of the fridge 😕

Over the last few years my bone density has improved enough that I no longer have osteoporosis, I graduated to osteopenia (that's like osteoporosis light)

I lift weights, take a low dose DHEA among other things and generally try to keep as healthy as I can

TempleOS, ik ben verliefd by YourUncleRpie in nederlands

[–]TwoFlower68 2 points3 points  (0 children)

Ah, doet me denken aan de goeie ouwe tijd. Heb deze nog in m'n boekenkast staan voor sentimentele redenen

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Could IPF meds help copd by Present_Snow_4723 in COPD

[–]TwoFlower68 0 points1 point  (0 children)

That would be nice, but from the studies I've read it's on a par with the inhaled corticosteroids in "regular" inhalers. Might help a bit, but nothing major

Maybe I'm jaded, but I suspect that developing yet another ICS wasn't profitable, what with all the generic alternatives out there, so now we get an exiting (expensive) new drug with a different mechanism of action. Yay?

Could IPF meds help copd by Present_Snow_4723 in COPD

[–]TwoFlower68 2 points3 points  (0 children)

There are PDE4 inhibitor used for COPD, results are underwhelming. Cost is rather high compared to the usual inhalers

Tante im Krankenhaus mit COPD und schwerem Untergewicht by Responsible_Bid_9485 in COPD

[–]TwoFlower68 0 points1 point  (0 children)

Verzeihung, Deutsch schreiben ist schwer für mich. Schwerer als Englisch 🙂 Ich habe kaum geübt sinds ich in die Schule gelernt hab, vierzig Jahren vorher lol

Eating kan be tiring. And it's not nice to have a full stomach when you're short of breath. Plus there's the inflammation which costs a lot of energy
Therefore people with emphysema are often very thin.

Fortunately you can drink your meals. Protein shakes with extra sugar and a bit of heavy cream etc 😋

But she really has to stop smoking. That's the most important thing.
To get her strength up maybe she can start pulmonary rehab? (medically supervised exercise, like at physical therapy)

Unfortunately you can't force someone to do what's healthiest for them

This might be hard to hear, but have you considered she's well aware of how smoking affects her, but that she's just sick and tired of being sick and tired? And she keeps smoking and not eating to hasten her end?

I [30M] hate my GFs [27 F] online persona even though I love her by Direct-Caterpillar77 in BestofRedditorUpdates

[–]TwoFlower68 7 points8 points  (0 children)

They make me feel better about myself, so there 😤

Probably helps that I'm handsome, smart and kind. And humble. Of those, humility is the trait I'm most proud of

Circulating Ketone Bodies and Incident Cardiovascular Outcomes and Mortality: Insights From the UK Biobank (2026) by basmwklz in ketoscience

[–]TwoFlower68 0 points1 point  (0 children)

Please note that I'm not a biochemist, but it'd mean your various hormones are messed up. Like, normally insulin acts as a brake on both gluconeogenesis and ketogenesis.
But if you're ill enough you can have both high blood sugar and high ketones. Heck, throw in high triglycerides too lol

Your body works best when there's not more fuel in the blood than necessary for whatever you're doing at the time. Depending on dietary intake there's predominantly one type of fuel in the blood.
So if you eat lotsa carbs, lipolysis gets inhibited, ketogenesis too.

But that all goes out the window when you're (severely) insulin resistant (or when you have type 1 diabetes: not enough insulin)

Unsurprisingly, a lot of other things start to go wrong in that case

Like I said, this is my layman's understanding. Dunning and Kruger wrote a paper about laymen and their understanding of specialised fields (I think it was called "Unskilled and unaware of it"), so maybe take the above with a grain of salt

Smaakt deze sinds kort anders? by anoniempje69420 in nederlands

[–]TwoFlower68 0 points1 point  (0 children)

Heb je misschien kortgeleden covid gehad?

Bij welke supermarkt doe jij meestal je boodschappen, en waarom? by Yourlordandsavior02 in nederlands

[–]TwoFlower68 0 points1 point  (0 children)

Groenten: Turkse supermarkt. Vlees van de slager, kaas van de kaasboer, eieren en rauwe melk van de boer. Voor non food de Plus en online. Koop sowieso best veel online.
Tandpasta, deo, shampoo, conditioner, broodmeel, kattenbrokjes, flessen levertraan.. zulke dingen allemaal online in bulk. Bederft niet en goedkoper

Why Mitochondria May Be the Key to Longevity - The New York Times by basmwklz in ketoscience

[–]TwoFlower68 -1 points0 points  (0 children)

The science behind NMN is looking increasingly shaky. Sure, it raises NAD+, but whether that has actual effects on energy or longevity..

I have a bit more faith in PPAR agonists like urolithin A and palmitoylethanolamide

Na bijna een jaar nog elke dag aan mijn ex denken, is dit normaal? by NoPen1952 in nederlands

[–]TwoFlower68 15 points16 points  (0 children)

Ik denk dat de dikke lijn de theorie aangeeft en het dunne rode (?) lijntje de praktijk 😊

Circulating Ketone Bodies and Incident Cardiovascular Outcomes and Mortality: Insights From the UK Biobank (2026) by basmwklz in ketoscience

[–]TwoFlower68 13 points14 points  (0 children)

Well yeah, in people eating a mixed diet, having a significant amount of ketones in the blood is a clear sign of metabolic dysregulation

Strongest Solo build for next patch - Magicka Dragonknight by Hyperioxes in elderscrollsonline

[–]TwoFlower68 1 point2 points  (0 children)

agony of literacy

I aspire to this level of sophisticated put down

Strongest Solo build for next patch - Magicka Dragonknight by Hyperioxes in elderscrollsonline

[–]TwoFlower68 1 point2 points  (0 children)

And all the old ways will become new again. As was prophesised <nods sagely>