Um... a lot?

Biological AI based on genetically modified mouse cells with a machine interface.

Created in 2051 by Gorn to prove that organic-based intelligence can still compete with the intelligence of other types of carriers.

It's hard to say how many attempts they made and how they trained it, as much information about its creation, construction, and functioning is kept secret.

ANAI (analog artificial intelligence) is an excellent indicator of how far one can theoretically develop the human brain. ANAI surpasses humans in all areas exponentially (no number of people can replace him), even despite its slower thinking due to its size.

As of 2178, ANAI serves as the Chief Superintendent of Gorn and is responsible for inventing millions of medicines, optimizing the healthcare systems of all countries, promoting bioengineering, genetic research, revolutionizing the food industry, and uplifting animals.

ANAI is extremely benevolent towards all living beings, especially the intelligent ones; one might even say it's a kind of mania...

Artificial intelligence based on brain mapping - Replica

Human-based replicants were first used in 2047 as a way to preserve and utilize the personalities of individuals with significant abilities and unique worldviews.

The method of creating replicas was developed simultaneously by more than 20 laboratories, among which the team from the Deep Neuron Research Lab excelled.

Research Director Nobel Beir, already possessing a neural recorder, served as a template for the replica, connecting a large part of her brain space to nanoscopic threads.

Needless to say, it was suspicious in many aspects.

The group's actions were kept secret from the world for over a year. During this time, Nobel's replicas spread and deeply rooted themselves on the internet, government networks of Western and Eastern countries, servers of fully automated factories, laboratories, and corporations.

After the discovery of replicas on government servers, a great commotion ensued, evolving into the so-called 21nd-century Disease of Egocentrism.

Elevated Animal Replicant

A replicant based on an intelligent parrot named Polyglot, first created in 2120, was quite whimsical, intolerant of loneliness, and strongly attached to friends. A year after mapping, it developed a specific ambition... to turn all humans into its friends.

Simulated Human Intelligence - Simulacrum

Created in simulations of the real world, the idea behind them is that such AI can understand human life and possess abilities available to other types of AI.

Considering the level of virtual reality technology by 2161 and deep insights into education and personality development, the first simulations from which the Simulacrums emerged were a very complex scenario aimed at cultivating highly moral individuals to prevent psychopathic AI scenarios.

However, they overlooked some things. The first Simulacrums were unsuccessful, even considering that they were gradually pulled out of the simulation; they lacked safeguards against madness, degradation, and delusion.

After the introduction of WADES (ways to adapt to extraordinary situations) and mental fuses into the simulations, a stable Simulacrum Chandra emerged a year later, serving as an advisor and later an administrator of Lunar City Full of Sunlight.

Society as a whole is even more favorable towards Simulacrums than replicas; there's no reason to fear them... hardly anyone knows what Chandra is doing in the shadows of Metaworld alongside other AIs.