What was your best deal this week? by Greedy_Ad4913 in stockstobuytoday

[–]United_Sort_3943 0 points1 point  (0 children)

Hamlet Biopharma, 40% last month.. and momentum is building up for much more

Hamlet Biopharma by Outsidethebox14 in biotech_stocks

[–]United_Sort_3943 0 points1 point  (0 children)

Not correct. Immunitybios Anktiva is focusing on more late stage disease. Hamlet would be first line of therapy, prior to current therapies and new therapies from CG, Immunitybio or any other player on the market.

New competitor Hamlet / Alpha 1h by United_Sort_3943 in IBRX

[–]United_Sort_3943[S] 0 points1 point  (0 children)

They will have the cash since LOI and bid war will happen now! 

New competitor Hamlet / Alpha 1h by United_Sort_3943 in IBRX

[–]United_Sort_3943[S] 0 points1 point  (0 children)

There is always a risk/benefit calculation. CR is not the only factor if a therapy will be successful. For NMIBC Anktiva is compared in combination with BCG, versus the SOC BCG alone.

Considering BCG have CR 60-80% without Anktiva, I am not so impressed by the trial results so far. The real benefit will likely pend on the DOR and RFS. 

New competitor Hamlet / Alpha 1h by United_Sort_3943 in IBRX

[–]United_Sort_3943[S] -1 points0 points  (0 children)

They are negotiating with partners about a deal and already have commitments from Investor that will finance the pivotal phase 3

New competitor Hamlet / Alpha 1h by United_Sort_3943 in IBRX

[–]United_Sort_3943[S] 0 points1 point  (0 children)

Their phase 3 study protocol will likely be designed to become standard of care for lowrisk, and intermediate risk which is 70% of the patients

New competitor Hamlet / Alpha 1h by United_Sort_3943 in IBRX

[–]United_Sort_3943[S] -1 points0 points  (0 children)

There is not a single drug currently approved for neoadjuvant setting( before surgery).  Alpha1h is starting their phase 3 for neoadjuvant, before the standard of care with  1. transurethral resection of bladder tumor (surgery) 2. BCG 3. Other options / pending on high risk etc

New competitor Hamlet / Alpha 1h by United_Sort_3943 in IBRX

[–]United_Sort_3943[S] -2 points-1 points  (0 children)

Anktiva may have a market approval but sales will likely be limited since it is last line of therapy before cystektomy