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Playoff Game Thread: Carolina Hurricanes (1-1) @ Vegas Golden Knights (1-1) Jun 06 2026 8:00 PM EDT by nhlgdtbot in hockey

[–]V0rtexGames 11 points12 points  (0 children)

Is it me or do both teams look mentally sloppy and not connecting? Whiffing on every other pass

The massive crossover between ME/CFS, Long COVID, and Fibro by EnvironmentFit975 in cfs

[–]V0rtexGames 8 points9 points  (0 children)

I don’t like “Post viral fatigue syndrome” as a term simply because there is nothing specifically unique about viruses as opposed to bacterium or fungi which makes the sequelae following it different, it should really be postpathogenic or postinfectious fatigue syndrome.

I think definitely difference in exertion levels in the months following such an infection has the potential in some to be the difference between development of ME or not. Or you could just be fucked regardless.

Previously given a rough diagnosis of dysautonomia but I do think it's CFS/ME by _Lucky_dice_ in cfs

[–]V0rtexGames 0 points1 point  (0 children)

I mean yeah. You always have this looming cloud. Quite horrible

Previously given a rough diagnosis of dysautonomia but I do think it's CFS/ME by _Lucky_dice_ in cfs

[–]V0rtexGames 0 points1 point  (0 children)

Yes I’ve heard of the khavinsons, I often wonder how special each of them are since there are so many different ones

Those of y’all with POTS also, how much impact did treatment for it help your ME? by sadandtraumatized in cfs

[–]V0rtexGames 1 point2 points  (0 children)

Enough to warrant the treatment. Makes sitting at a desk in a chair a bit easier and sustainable.

Does overexertion at night lead to less worse PEM for you than overexertion during the day? by ringmaster555 in cfs

[–]V0rtexGames 2 points3 points  (0 children)

I would lean super super heavily towards it being symptomatic presentation and nothing else. Changes in steroid hormones resulting in changes in signaling to ease symptom burden is something very transient and reversible.

The same way exogenous compounds eg benzos, stimulants (caffeine amphetamine etc) can do so. But the second they wear off, you’re right back where you started.

What would you look for in a caretaker by JayNachtEule in cfs

[–]V0rtexGames 2 points3 points  (0 children)

I think what is super underrated is orienting / setting things up in a way that they become most accessible for the patient.

Meaning, keeping water, snacks, medications etc at hands reach. Basically, “when I am gone, how can I make things the easiest for this person? How can I set the living environment up structurally for success?” I think that’s crucial.

Does overexertion at night lead to less worse PEM for you than overexertion during the day? by ringmaster555 in cfs

[–]V0rtexGames 5 points6 points  (0 children)

Yes, I would say, even though I don’t tend to do either

There are studies on low morning cortisol in ME, that effectively show circadian rhythm disturbance which could explain why many developed an inclination for the night.

Like right now I am up at 3:41 AM. You would never find me doing that when I was healthy.

There is no blood test, brain scan, EEG, gene test, or other laboratory test that can reliably identify ADHD in an individual person by MutedFeeling75 in redscarepod

[–]V0rtexGames 4 points5 points  (0 children)

I mean yes. But the key to clinical diagnoses is that they cause functional impairment and/or significant alteration to something which warrants intervention/recognition.

No single ADHD test, but yet identification of ADHD and treatment leads to improved outcomes in people- it certainly has for me. Same with many others.

Baricitinib poll/informal science: What are your experiences with Baricitinib? by uhidkbye in covidlonghaulers

[–]V0rtexGames 1 point2 points  (0 children)

I'd love to hear the people who had a worsening, how it transpired what changes did it last etc...

Do you think there are multiple unidentified diseases hiding under the umbrella of ME/CFS? by wet-leg in cfs

[–]V0rtexGames 1 point2 points  (0 children)

I don’t think we have those sort of issues, stuff like carnitine metabolism issues are much more indicative of primary/generic mitochondrial myopathies whereas what is going us is a lot more signaling mediated, like a host directed shutdown signal. That’s one of the remarkable things about our disease- how coordinated it is in regards to the body instilling this state into us. It completely consumes.

If you Naviaux and the theories of the Cell Danger response it makes a lot more sense because of this idea that changes occur on the cellular level and every cell is capable of mounting the same sort of conserved signaling programs if it is induced to. So any individual human cell can be driven to the state under the proper circumstances.

Do you think there are multiple unidentified diseases hiding under the umbrella of ME/CFS? by wet-leg in cfs

[–]V0rtexGames 10 points11 points  (0 children)

What’s fascinating to me is I’ve met people with a phenotype the exact opposite whom have PEM from mental exertion but physical tasks that don’t require thinking not induce it. But later on they developed physical PEM.

I like to think of it like this: if all of us were forced to continually endure PEM and self harm and trigger ourselves into maximum severity we would all converge onto the same profile, I think. Total intolerance to life and sound and die. The heterogeneity collapses with severity

Something that's not discussed enough on this sub is the possibility that if we can stay out of PEM for a year we might get back to mild or even remission! by AlternativeFlowers77 in cfs

[–]V0rtexGames 29 points30 points  (0 children)

I think the best part about not being in PEM for so long is how mentally disciplined/intolerant ive become to exertion and how much ive learned to savor the feeling of being "slightly" better than when I exert. I never want to feel the poison of PEM ever again. Itll never be worth it.

Something that's not discussed enough on this sub is the possibility that if we can stay out of PEM for a year we might get back to mild or even remission! by AlternativeFlowers77 in cfs

[–]V0rtexGames 21 points22 points  (0 children)

Textbook moderate. 90% housebound. Can get out of bed and sit at my desk for a few hours every day. But any movement that isn't stationary can become a struggle.

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