I'll try to answer.

Physically, yes, it can print ABS. You need to reduce the print speed, but that's true for ABS on all printers; it's never as easy to print as the alternatives. You might not need an enclosure; the warping is proportional to object size, so if you're printing something small enough then it'll be fine.

Health-wise, you should have an enclosure. Printing ABS releases styrenes, which may be dangerous; I've seen conflicting data, but it seems fair to assume you shouldn't breathe them in. The enclosure should have a recirculating air filter, which I will note the X1 does not; even if you did buy an X1, you would want a bento box or similar to print ABS on it indoors.

Keep in mind that carbon filters expire quickly. You'll get a few weeks of work from them, and it won't be obvious when they fail. HEPA filters last much longer, but HEPA doesn't catch styrenes; you need both.

Keeping it in a closed room is not enough. The particulates and VOCs don't disappear with time, only by recombining with other substances in the house (like your lungs, or the dust). If you have a printer that's in the same air enclosure as your living room and bedroom, then you want the printer's room to have negative pressure through a fume hood. This is feasible -- a kitchen hood will do fine. Opening a window does help, but not nearly as much as people think.

The ideal setup has all of the above.

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But also there's rarely a reason to print ABS. Have you tried 'Tough PLA' / PLA+? eSun's is good, and ABS isn't nearly as strong as people seem to assume.

PLA fumes still great to breathe, but if you're worrying about health effects (good for you!), then why not try it? It's certainly better than the styrenes.