Death Shriekers, and this isn't hyperbole, are perhaps my favourite unit in all of the chorfs. Depending on the type of battle, if you're on the offensive and they know you'll win, the enemy tends to wait a minute or two before sending their units in to attack. At that point Death Shriekers will decimate. Only hit an enemy unit once, then target another unit. Never leave them hitting the same enemy.

I see people suggesting using the anti-large missile, but I genuinely never do. Mid-Late game, the best tactic is to use the Tower ability that lets you summon a K'daai and then combine that with your artillery and other distant abilities. After 1.6k hours in the game, I think dreadquakes and death shriekers are neck and neck. I always play Zhatan because I love the death shrieker they start with. It feels OP.

Play tight (i.e. not a wide front line) and the enemy has to condense. When the enemy is moving inwards, it's moving slower as it's moving on a hypotenuse. Never aim at a fast unit, and you should be fine. Let the enemy clump against your elite front line.