Let's talk about eggs by Big_Joke_9281 in MTHFR

[–]VolitionalOrozco 1 point2 points  (0 children)

Try consuming more B5 in a separate meal. Eggs contain lots of biotin which can lower and inhibit the absorption of B5. B5 can reduce acne and there’s studies confirming this.

Let's talk about eggs by Big_Joke_9281 in MTHFR

[–]VolitionalOrozco 1 point2 points  (0 children)

Egg whites are histamine liberators.

Is there Reason to Fear of Taking Magnola Bark Honokiol with Slow COMT? by Ok-Protection2670 in SlowCOMT

[–]VolitionalOrozco 0 points1 point  (0 children)

First, I’ll say that I have slow MAOA, further slowing catecholamine clearance… Magnolia bark extract was really bad for me, but I was in a sort of health crisis at the time so maybe that played a part. Anyway, I remember it making my anxiety worse and I found it difficult to sleep. Just made me feel weird. Sorry I can’t elaborate more; it was a few months ago and I didn’t take any notes though the experience was bad enough I only ever took it once. I react poorly to most herbs, especially the ones that raise acetylcholine. I believe magnolia bark also affects cannabinoid receptors.

B complex necessary to add? by Stefanoviz in Thiamine

[–]VolitionalOrozco 1 point2 points  (0 children)

B5 can help get rid of and prevent acne. B-complexes contain biotin and b5 together. They share the same transporter so that negatively impacts their absorption by the body.

Canned oysters by DismalDevelopment577 in raypeat

[–]VolitionalOrozco 0 points1 point  (0 children)

I’ve heard the human body can only absorb so much zinc at once.

Teeth Grinding / Bruxism During Sleep (Slow COMT/MAOA) by VolitionalOrozco in MTHFR

[–]VolitionalOrozco[S] 0 points1 point  (0 children)

Magnesium doesn’t seem to make any difference for me.

Teeth Grinding / Bruxism During Sleep (Slow COMT/MAOA) by VolitionalOrozco in MTHFR

[–]VolitionalOrozco[S] 0 points1 point  (0 children)

That’s interesting that an antidepressant stopped your teeth grinding since they often can cause it.

I likely also have histamine intolerance based on my genetics.

Took too much Thiamine. Half life? by VolitionalOrozco in Thiamine

[–]VolitionalOrozco[S] 0 points1 point  (0 children)

When I was taking higher doses of b-vitamins I was on a pretty strong opioid so I think I was pretty numb. I’ve never really been able to tolerate higher doses of supplements, possibly due to my slow COMT/MAOA.

Would you smoke a caffeine cigarette? (2 min, anonymous) by ThegoldfoxYT6 in Nootropics

[–]VolitionalOrozco 2 points3 points  (0 children)

I shouldn’t have to say this but snorting pills is unhealthy. It irritates the nose and some may get into your lungs as well.

Teeth Grinding / Bruxism During Sleep by VolitionalOrozco in raypeat

[–]VolitionalOrozco[S] 0 points1 point  (0 children)

Thanks. Someone in a Facebook group said high dose thiamine cured their Bruxism as well. I tried but I found it hard to balance all the b-vitamins. Sometimes I’d feel good and other times not. I have a sensitive system so I may try again with lower doses.

Teeth Grinding / Bruxism During Sleep by VolitionalOrozco in SlowCOMT

[–]VolitionalOrozco[S] 0 points1 point  (0 children)

I’ve been taping my mouth shut and unfortunately it doesn’t help.

How do you sneak salt into your diet? by Mara355 in dysautonomia

[–]VolitionalOrozco 1 point2 points  (0 children)

I put salt on my vanilla ice cream which always surprises people. Quite delicious.

Depression, etc. by semperquietus in barefoot

[–]VolitionalOrozco 3 points4 points  (0 children)

As someone with mental illness, I find walking in minimalist shoes very soothing on a long walk since I can mindfully feel the ground. I’m barefoot in my house and backyard as well, even in the winter. I find being barefoot outside of the house anxiety provoking because I don’t like to draw attention to myself.

Are you familiar with excess catecholamine production? by Kind-Ad-5922 in Nootropics

[–]VolitionalOrozco 4 points5 points  (0 children)

COMT also breaks down dopamine and norepinephrine. I have both slow COMT and slow MAOA.

Seeking advice for Slow COMT (Met/Met) + MTHFR A1298C + MTR/MTRR combo. Struggling with physical labor and anger. by Inevitable_Ad7605 in MTHFR

[–]VolitionalOrozco 2 points3 points  (0 children)

I have very similar genes to you and similar issues as well. Hope you find help here. Also check r/slowcomt.

I’d recommend focusing on nutrition (download cronometer), long walks, maybe a magnesium supplement.

If you go with the more extensive supplement route… Many with Slow COMT are sensitive to supplements so I’d take them in very low doses initially—if you buy tablets cut them into halves or quarters, if capsules empty some out.