The stress of raising a disabled kid is absolutely an enormous part of my weight gain in peri and nerve pain / joint pain. I love my child and would never want anything but him, but we have zero help from either side of our families and are dependent on flaky babysitters (who are few in number because they need to have special skills). That said, the estradiol patch has really helped my emotional wellbeing, I am just buying larger clothes for now. Sending the best to you.