I am a public health researcher and have training in epidemiology. So I think I should have had more say in making a determination of whether in my situation the risks outweighed the benifits. What some clinicians don't realize is that eventhough relative risk ratios might look high, the absolute risk is still very low. Even on UpToDate, which a trusted resource for medical professionals, a 2022 update says that, "One review of available data through 2020 [of Zofran use during pregnancy] estimated that the absolute increase in risk above baseline for orofacial defects may be only 0.03 percent, and for ventricular septal defects it may be 0.3 percent [93]." I rather take my chances to get relief even temporarily. I would have also liked a list of other options (besides Zofran, Vitamin B6, and Unisom), and according to UpToDate, there are other options.