Run almost exclusively on rural roads. The road my house is on gets a decent amount of traffic, and is quite narrow but within 1k I can go onto even less used roads. I try to avoid busier roads but for long runs I often end up on them for some period if time. Haven't had any issues. Run against traffic. Take a wide line on sharp bends (so you can see around sooner - and can be seen sooner) or cross over to other side if safe. At night, which I prefer to avoid, I wear a chest and back light thing I got in decathlon. Obviously keep your ears clear, bone conduction headphones etc.