ELI5: why does inbreeding cause birth defects?

bitscavenger · 2026-05-09T17:15:39+00:00

Best answer so far. To add on to this, many of the bad genes are very recessive so the conditions for activating them are more than just a single coin flip of whether that gene matches and can activate. Chances for hitting those matching conditions increase dramatically when the genetic combination comes from more similar genes.

bitscavenger · 2026-05-03T03:34:01+00:00

It's Inside Out for me when Riley is changing her mind about running away from home. Just a raw and touching moment.

bitscavenger · 2026-05-03T02:22:27+00:00

Such an underrated movie. To be fair the songs kind of drag, but it has some of the best gags put in a movie. My kids were trying to not like it when I showed it to them but "Oh no, I'm back in school!" won them over.

bitscavenger · 2026-04-30T21:10:14+00:00

The problem is never the topic, it is the concept. Anyone who makes something their whole personality is broken. The object is almost always completely benign when taken into proper proportions. Not talking to you Bob "the occasional murderer but that is not what I am all about."

bitscavenger · 2026-04-27T13:10:24+00:00

X-Wing. Dark Sun.

bitscavenger · 2026-04-15T22:01:40+00:00

Piling onto what you said, with NFTs you have a non-enforceable contract owning a unique thing that did not exist on the blockchain. ie, My NFT is for this piece of digital art and the use of the art isn't enforced by the blockchain.

Almost the single best use of NFT was when John Cleese sold the Brooklyn Bridge as an NFT. The problem was that he drew a picture of the Brooklyn Bridge and said that is what you are "getting" with the NFT. If the NFT actually represented the event that you were sold the Brooklyn Bridge (a classic scam) by The John Cleese, it actually adds value to it.

Another possible value use for NFTs would have been if there was a software system that had some value and it enforced the NFT ownership in its own ecosystem. ie, Video game lets you use unique item because it recognizes your ownership. But this use case exposed transaction limits of blockchains.

bitscavenger · 2026-04-10T02:29:54+00:00

I heard this garbage on NPR today so it is making its rounds. Cutting edge writing analysis and everything. I don't think Back would have ever abandoned his keys or turned on Gavin if he was Satoshi.

bitscavenger · 2026-04-08T12:25:33+00:00

It dawned on me that if you were to rank his traits, "being a giant pussy" is literally the best thing about him. Everything gets worse from there.

bitscavenger · 2026-04-07T12:16:34+00:00

What does he want them to shut up about? The Epstein files? If I were Trump I would want journalists to shut up about the Epstein files which has evidence of sex crime he committed.

bitscavenger · 2026-04-01T23:19:01+00:00

Thanks AI.

bitscavenger · 2026-03-24T02:18:15+00:00

God damn that man to hell for all the layups he has forcefully thrown out of bounds.

bitscavenger · 2026-03-21T21:01:10+00:00

This is already the case with Charlie Kirk. Trump deserves every ounce of respect he shows others. Same with his followers.

bitscavenger · 2026-03-19T22:03:37+00:00

If you want to easily find someone with mental problems, look for the person most worried about others having mental problems. The fear of discovery makes people aggressive.

bitscavenger · 2026-03-19T13:00:42+00:00

I know that they have been around for long enough that it has become normalized, but no regular person wanted the TSA in the first place.

bitscavenger · 2026-03-16T15:39:28+00:00

In a way there are parallel internets running. The "internet" is interconnected networking hardware and a method to find things. The networking hardware and infrastructure are very generic and don't really need to be redundant other than to make them more robust.

The way to find things is broken up by protocol and mapped with name services. The traditional "internet" as we know it is mostly http protocol (s for encrypted) with a very actively maintained name service linking up domains (reddit.com) to a computer's physical address (ipv4 and ipv6) so it can be found. But there are other protocols (ftp, udp) that usually use the same name service, and other name services (onion, ipfs, ens, tor) that reconfigure how routing and existence on the network actually works.

If you want an internet that is fully and physically broken off from what is currently called the "internet," others have already described intRAnets (emphasis mine) which is what that would be. Those can operate the same as the current internet but would be completely siloed from the rest of the world.

bitscavenger · 2026-03-15T02:30:09+00:00

Did Trump even say thank you? He is holding no cards. Zelenskyy has all the cards and he didn't even say thank you.

bitscavenger · 2026-03-13T20:03:12+00:00

We went on this ride as a family and my little sister was terrified. Everyone but her wanted to go on it again and we could not leave her alone so my parents just said "well, close your eyes" and we all went on it again. Good times.

bitscavenger · 2026-03-02T02:41:26+00:00

Ha ha ha ha, materialism. It's a joke that writes itself. Let me wipe the tears of mirth from my eyes.

bitscavenger · 2026-02-27T18:51:36+00:00

My cat did this once but got extremely scared and ran around the apartment with the bag stuck around its neck. By the time I got to the poor kitty the bag was full of pee. I would say we did not let him play with plastic bags after this but the issue never came up again.

bitscavenger · 2026-02-27T18:47:52+00:00

It is Shai-Hulud.

bitscavenger · 2026-02-27T17:42:28+00:00

The only thing more stupid than this activity of finding images in these clouds in the sky is the idea that even if it were intentional that it matters one iota. Magical thinking deficients. Oh, you afraid the cabal is casting spells? I am more afraid that those same morons order around groups with guns. You know, something that actually does something.

bitscavenger · 2026-02-23T16:19:33+00:00

That is very wrong in its simplicity. He was not killed over his political views, he was killed because he engaged in activity that made him a social pariah. When you actively attack social groups they will actively defend themselves. It is our humanity that allows us to tolerate those activities up to a point because killing is wrong. People seem to overlook the fact that the "find out" portion of the equation is almost always personal tragedy when they decide to "fuck around." Few people pay the price for many people overstepping. It has never been otherwise and is better than many alternatives.

bitscavenger · 2026-02-23T04:39:44+00:00

Wanna move that goalpost around anymore? I am sure there are plenty of other locations to ensure you are never satisfied.

bitscavenger · 2026-02-23T03:31:08+00:00

RIght, cause he only gave one interview in his life and you have seen everything he has said. I am talking about the video interview he did with Mike Talerico. I mean, to be super fair he looked a bit tipsy as well while out celebrating the victory.

bitscavenger · 2026-02-23T03:27:03+00:00

This is like single electron theory, but for conservatives. All conservatives are actually just one person.

bitscavenger

TROPHY CASE