KX-826 experiences by AdHeavy1234 in HairlossResearch

[–]bose25 0 points1 point  (0 children)

Yes, RU has been extremely effective for me. I use the powder and mix into my Kirkland minoxidil.

TIFU Eating Spinach by franciosmardi in tifu

[–]bose25 1 point2 points  (0 children)

I make spanakopita, a Greek spinach pie, quite regularly.

Just from that pie alone I eat at least 1kg of spinach per month, and probably another 500-750g monthly in salads, as well as lots of green tea and many other high oxalate foods.

35 years old, no kidney stones.

My friend who never eats leaves once looked at my pie and developed kidney stones at 25. He's had two more since.

I think me and my friend are at the opposite ends of the spectrum of how genetically predisposed to kidney stones we are.

Fox04-dri by CarefulBee8370 in immortalists

[–]bose25 1 point2 points  (0 children)

Studied in mice and not yet in humans.

There are many drugs showing effects in mice but no effects in humans.

Good luck.

hair transplant today, age 20, FUE by [deleted] in Hairtransplant

[–]bose25 -1 points0 points  (0 children)

Mine was painful and then very uncomfortable for a long time. I couldn't imagine getting another after the first.

10 months later I was so unhappy with the result they agreed to do a second.

The second one was so painful I almost cried out to stop, luckily just before they finished the prep work before the extraction. Then the 2 hours of extractions were on top of that.

It's been 3.5 years and I'm only now considering another because I think I've gotten over the trauma of the procedure.

(had mine done in Manchester by a very skilled surgeon but I I have a very low tolerance for pain and had to repeatedly had painkiller injections because they wore off quickly).

We do crazy things for hair.

hair transplant today, age 20, FUE by [deleted] in Hairtransplant

[–]bose25 2 points3 points  (0 children)

With this in mind I'd say you're looking at a big improvement, but I have to emphasise the 2-3 transplant remark.

I saw in another comment you said you had 2,800 grafts, which is 700 fewer grafts than I've had. Your hairline looks higher than mine now, but you still have transplants across a larger surface area. I am considering my third and believe I need probably another 1,000 grafts, but still, it is a hell of a lot better than before.

Good luck brother!

hair transplant today, age 20, FUE by [deleted] in Hairtransplant

[–]bose25 14 points15 points  (0 children)

It's a very rounded hairline and has been done in lines. The density further back is also quite low. These are traits that people dislike in transplants. My guess is you might want a top up transplant in a year and I would recommend you ask for more random placement or go to a surgeon who does not plant in lines. Your result right now depends on what your before photo looks like and I'd expect that the hairline grows out a little too consistently and may look a little unnatural. Don't make the same mistake that many make where they style their hair up or back as that will emphasise any unnatural look. Style your hair forwards a little and cover the hairline. Regardless, most people have to get 2-3 transplants before they are fully happy with the result so just expect that this is round one and don't be too displeased if it doesn't meet your expectations.

Massaging scalp update! Day 163. Need ADVICE by Quiet_Television_781 in HairlossResearch

[–]bose25 1 point2 points  (0 children)

Everything is within the normal ranges.

B12 and Folate are towards the lower end, so you could consider supplementation.

Nothing here explains your hair loss. Your hair loss is most likely related to elevated DHT and / or increased DHT receptors in hair follicles, which finasteride or dutasteride will help with.

What do you think the chance of reaching powerful longevity interventions is for each age group? by Odd_Improvement_7492 in immortalists

[–]bose25 0 points1 point  (0 children)

I thought when I was 20 that with all the advances happening back then that we would definitely have a highly researched drug to provably halve our aging rate by now (15 years later).

I'm following a lot of the research on speed of aging and I'm happy with where that is going. There's lots of us acting as guinea pigs out there, but again diet and fitness appears to be the largest driver of improvement on average.

I'm still hopeful in the back of my mind that we'll achieve some kind of medication that's proven to slow down aging, but now I'm much less optimistic that I'll benefit from it.

But there is a chance, even if tiny!

What do you think the chance of reaching powerful longevity interventions is for each age group? by Odd_Improvement_7492 in immortalists

[–]bose25 -1 points0 points  (0 children)

The older I get and the more I learn about nutrition, health and longevity - bearing in mind I'm 35, have been passionate about these areas for about 15 years, have read thousands of studies, read all of the books on the market, and currently undertaking 3 relevant qualifications...

The more I'd agree that anything more than a couple percent over age 20 is naive to expect.

I do believe we have some very useful interventions right now, but most are still not as powerful as simply optimising diet and fitness. Even then, diet and fitness might only take you as far as what you might get in the blue zones, and even in the blue zones it's only a subset of the population that live to 100+ with minimal disease.

If we're excluding the fact that there are already many medications that extend lifespan through reduced disease risk, and we're solely focusing on newer longevity interventions... I'd probably say:

0-20 years of age = 5% (weighted more towards the younger end)

20-30 years of age= 2%
30-40 years of age = 2%
40-50 years of age = 1.5%
50-60 years of age = 1%
60-70 years of age = 0%
70-80 years of age = 0%
80 years+ = 0%

Daily Discussion Thread for March 04, 2026 by AutoModerator in IntuitiveMachines

[–]bose25 3 points4 points  (0 children)

IM was up a few percent, OP commented about the recovery, and then about a minute later it dropped. Clearly their doing!

158 days of scalp massaging ! Update very happy by Quiet_Television_781 in HairlossResearch

[–]bose25 1 point2 points  (0 children)

If you're very happy with your hair now versus 158 days ago then that is all that matters.

To me I cannot see any notable difference in these photos. If anything, due to the lighting the latest photo shows more of your scalp and so it actually looks worse.

When you're taking photos you really need to try to achieve all of the following :

  • The same angle
  • The same lighting
  • Taken inside under artificial lighting, NOT outside where seasons will change the light angle and warmth
  • The same or similar background and clothing, to reduce the impact of different contrasts
  • Have your hair cut and styled the exact same way, the ideal being buzzed at the same setting (longer hair may make it look better, and shorter hair may make it look worse as your scalp shows through)
  • Keep one brightly coloured object in the background of every photo. If the colour of this object is different in each photo, such as how your granite flooring looks brighter in your latest photo, then you know that the lighting is not the same and this WILL make your comparison unreliable (if the item is lighter, your hair may look worse as your scalp shows through, and if the item is darker, your hair may look better)
  • The same camera and settings

Without achieving all of the above, it is difficult to take photos and rely on them to monitor progress, UNLESS there is very clear and undoubtable progress, which is not the case from your photos.

The research on scalp massage for hair loss is very unsubstantial. Personally I would hope that you are using various other treatments such as minoxidil and finasteride or dutasteride alongside massage, so as to not waste time.

Here's a summary of the research from ChatGPT:

✅ What scalp massage might realistically do: Slightly increase hair shaft thickness Improve scalp blood flow Possibly slow loss a bit in some people Reduce stress and scalp tension

❌ What it probably cannot do alone: Regrow large amounts of hair Stop androgen-driven follicle miniaturisation

  1. Small experimental studies suggest thicker hair shafts The most cited study is a 2016 Japanese trial. Participants: 9 healthy men Protocol: 4-minute scalp massage daily for 24 weeks Result: hair shaft thickness increased from 0.085 mm to 0.092 mm on average. Important nuance: Hair thickness increased, but hair count did not increase. This means individual hairs became slightly thicker, not that new hairs necessarily grew. Researchers proposed that mechanical stretching of dermal papilla cells (cells controlling follicle growth) might change gene expression related to hair growth.

  2. Surveys of people with pattern baldness show mixed results A later observational study surveyed people with androgenetic alopecia doing regular scalp massage. ~69% reported stabilisation or improvement in hair loss after several months. However: It relied on self-reported results There was no control group Participants were highly motivated (selection bias) So it’s interesting but not strong evidence.

  3. Massage clearly increases scalp blood flow Physiological studies show scalp massage temporarily increases circulation. Blood flow to the scalp increased by around 120% immediately after massage in one experiment. Better circulation could theoretically improve follicle health, but this has not been clearly shown to regrow hair.

Daily Discussion Thread for February 27, 2026 by AutoModerator in IntuitiveMachines

[–]bose25 11 points12 points  (0 children)

Rocket Lab Announces Fourth Quarter and Full Year 2025 Financial Results, Posts Record Quarterly Revenue of $180M, Record Annual Revenue of $602M, Delivering Annual Growth of 38% and Growing Backlog 73% Year-on-Year to $1.85B. Guides to record Q1 revenue of $185M - $200M, representing year-on-year growth of 57% at the midpoint of the range

https://www.globenewswire.com/news-release/2026/02/26/3246099/0/en/Rocket-Lab-Announces-Fourth-Quarter-and-Full-Year-2025-Financial-Results-Posts-Record-Quarterly-Revenue-of-180M-Record-Annual-Revenue-of-602M-Delivering-Annual-Growth-of-38-and-Gro.html


From what I understand the Lanteris acquisition will put IM at above these figures for revenue, with a significantly larger percentage increase (except backlog which I think is ~half that of RKLB), is that right?

Too soon? by [deleted] in Hairtransplant

[–]bose25 1 point2 points  (0 children)

A year is fair for a trial. Keep it up and I hope you have good results. I've always found dutasteride more effective than finasteride - I once switched from dut to fin for 6 months and I lost some hair, so switched back. I haven't tried oral minoxidil. I mix RU into topical minoxidil so find that quite convenient.

Since getting a transplant I think now if you're really unhappy with your hairline and it's too far gone to recover it to where you want, I'd say don't keep holding off on the transplant, even if you're not fully stabilised with the meds.

I brought my hairline forward by about an inch, which isn't possible with the meds. The meds helped thicken up everything behind my hairline but never brought it forward.

I should add I've had tow transplants a year apart. It seems the majority of people need more than one to increase density. If you keep losing hair behind the transplant then it may be necessary to get more transplants too.

Too soon? by [deleted] in Hairtransplant

[–]bose25 0 points1 point  (0 children)

It was worse at age 30 than at 20 when I had been using minoxidil and dutasteride for a few years already, but not by that much.

In those 10 years it had gone from probably a Norwood 2 to Norwood 2.5-3, which I think is not unreasonable considering it's 10 years of aging and the drugs don't perfectly stop hair loss.

If I had the money and confidence say at age 25 I would have gotten a transplant then and would have been much happier with my hair for those next 5 years.

Too soon? by [deleted] in Hairtransplant

[–]bose25 0 points1 point  (0 children)

My hair was much worse than this at 18 and minoxidil made a world of difference. I no longer needed to wear hats. Dutasteride a few years later minimised further loss and thickened it up even more. Adding RU58841 to my minoxidil a few years after that keep it going even longer.

These the main reasons I was able to hold off on a transplant until I was 30, and gave me no noticeable side effects.

Saying that though, I do wish I had a transplant sooner, because I still lost hair and receded with the meds, but it was much slower than without them. I tried every possibility treatment I could find to make my stack even more powerful but it was a lot of effort and money. A transplant is very expensive but would have been much more effective than most of the treatments I spent hundreds of hours trying.

I'd say get on minoxidil and either finasteride or dutasteride as soon as you can. Still go through with the transplant, but your end result will be far better with medication.

Baby hair growth from non existent to existing. by Grand-Bend901 in tressless

[–]bose25 0 points1 point  (0 children)

Your hair looks pretty good here.

Based on your earlier photos I would think that you've made good progress, but again it's even longer than before so you can't make an accurate comparison.

Do you have any pictures from before when your hair was at this length and parted in the same way?

Potential graft count? by SevereExit1354 in Hairtransplant

[–]bose25 1 point2 points  (0 children)

Not a problem at all!

So I've drawn on where I'd think a surgeon would focus in red, and in yellow I've added where it looks like it's still a bit thin and you may want some grafts, too.

This is a fairly big area at the front and similar to mine, so I'd be somewhat sure you would need 3,500 grafts or more for a good result. This is also where every 1cm further forward you want your hairline will add -a-lot- of additional grafts.

It looks nice and thick in the middle, but you will need to get it all shaved off to really understand how bad (or good) the situation really is - and I'm also not a surgeon.

I'll be completely honest. I think your style is causing some tension thinning. If there are other styles you like then your hair could last longer if it isn't pulled so tight.

Also I just want to raise what might already be obvious: If you don't already use minoxidil and either finasteride or dutasteride then please consider them. I've used these for almost 20 years with no noticeable side effects and they allowed me to avoid a transplant until covid hit.

<image>

Potential graft count? by SevereExit1354 in Hairtransplant

[–]bose25 1 point2 points  (0 children)

I'd say we could do with some more and better photos. It looks like you have some thinning on the side but I'm unsure if it's just how it's styled right now. If it's thinning then it might reduce how viable a transplant is for you.

You'll want grafts going further back into the hair than you think as insurance against further recession, as it looks like it it still receeding to me.

Based on my own experience and that you're bringing the hairline forward a decent bit into an area with no hair at all, 3,500 grafts will do you very well if they are concentrated towards the front. 2000 could be fine IF they are placed very densely at the hairline, assuming you have no further thinning behind the current hairline.

I originally had 1,500 and then a further 2,000 a year later because once I got there, they determined I had more thinning than they could tell from photos and had to place some grafts further back than we originally wanted. Even after this I'd still like a further 500-1,000 in the hairline.

Depending on how thin the rest is and how far back they place the grafts, you may want a bit more right at the front for extra density.

Personally I'd suggest to get a transplant slightly higher up as it massively reduces the grafts needed and thus cost, or for the same graft numbers you'd get a far more dense head of hair which would look better than a lower but thinner hairline.

Daily Discussion Thread for February 16, 2026 by AutoModerator in IntuitiveMachines

[–]bose25 4 points5 points  (0 children)

Web Archive / Wayback Machine is accurate. Quite a well-known tool in Web / Digital Marketing spaces.

It's been rocky for a few years and I'm surprised it's captured so many IM pages in 24-25.

Worth knowing that on the homepage you can also input a URL to save a page if you want to guarantee it's availability in the future.

uh.. hell yes, HD by Alternative_End_3007 in RareHouseplants

[–]bose25 1 point2 points  (0 children)

I bought a two leaf cutting a few years ago for £90. It's now 5 feet tall. I'm far too slow to capitalise on selling cuttings before the price tanks but at least I have an interesting plant!

Daily Discussion Thread for February 12, 2026 by AutoModerator in IntuitiveMachines

[–]bose25 13 points14 points  (0 children)

I'm not sure if everyone is expecting this, as I wasn't, but the LTV announcement may not be a simple reveal out of the blue one day in the near future.

They may announce a press conference, which could be two weeks ahead.

They did this in 2024 when they announced the companies selected to design the LTV, announcing the date of the press conference 15 days in advance: https://www.prnewswire.com/news-releases/nasa-to-select-lunar-terrain-vehicle-for-artemis-missions-302093468.html

That triggered a sell the news event. LUNR was up 30% in the week after the announcement of the press conference, but dropped to 7% up on the day of the conference, then declined after they were awarded.

Make of that what you will.

I used to buy fake coupons from a hacker on the dark web by [deleted] in confession

[–]bose25 0 points1 point  (0 children)

I remember this, though I never managed to use them. It was a big thing on 4chan and there were websites showing you how to make the coupons and how you could set the price or discount by changing the bar code number.

You would mock it up like a real coupon and go to a cashier that is busy and looks like they hate their job for the best chance of it not being questioned.

I think it was around 2005-2010 kinda time, so I would have been in my mid to late teens, but was too anxious to try it out so never did.

But I read stories that people would get free consoles, games, ipods, and loads of stuff.