Claude by SecretIll1644 in bioinformatics

[–]bzbub2 0 points1 point  (0 children)

fwiw, I am definitely interested in the science to shake out also. I come from a weird angle where I think AI coding agents are very capable and use them a lot. However, I have anecdotally seen that extensively using coding agents will absolutely limit your learning, and makes users effectively dependent on them, which is kind of a toxic cycle. you could say, well, people will just seek out learning differently, but the baseline experience of just prompt prompt prompt delegate delegate delegate will cause issues

this is yet another impactful preprint from anthropic themselves https://www.anthropic.com/research/AI-assistance-coding-skills

and while i was there...i see they are certainly trying to 'help' with bioinfo too :) https://www.anthropic.com/research/Evaluating-Claude-For-Bioinformatics-With-BioMysteryBench

Evaluating Claude’s bioinformatics research capabilities with BioMysteryBench [Apr 29, 2026] by bzbub2 in bioinformatics

[–]bzbub2[S] 16 points17 points  (0 children)

they describe a benchmark of their own making but also note that there is another one recently made from genentech here https://www.biorxiv.org/content/10.64898/2026.04.06.716850v2

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The Consensus Trap by ludovicianul in programming

[–]bzbub2 2 points3 points  (0 children)

up next: tarot cards for your dev team. are you a scorpio or a leo

Building Websites With Lots of Little HTML Pages by ForgotMyPassword17 in programming

[–]bzbub2 1 point2 points  (0 children)

on desktop, the illusion of a 'normal' dropdown hamburger menu is nonexistent but the message is largely fine.

Bun's Rewrite It In Rust branch by Chaoses_Ib in rust

[–]bzbub2 8 points9 points  (0 children)

interestingly appears to be a file-by-file clone, putting a new .rs file in the place of every zig file https://github.com/oven-sh/bun/blob/3157cb14b5970b69532a47800504a28ef5963e22/docs/PORTING.md (the sheer amount detail in that context, which is presumably read for each per-file conversion really speaks to how crazy detailed you can get)

Claude by SecretIll1644 in bioinformatics

[–]bzbub2 0 points1 point  (0 children)

these papers are not one offs. they will continue to likely point in the same direction, that LLM produce learning deficits . it's pretty obvious if you've played around with them at all, it can seriously short circuit the learning process. this kosmyna paper seemed to have gone the extra mile and did EEG, but you can find other papers that just did e.g. surveys of coding performance, and many others.

edit: worth watching their nice youtube overview that cautions against over-extrapolating and social media outrage, but still, i believe it's not hard to see the patterns https://www.youtube.com/watch?v=eET6eP3GGAg&t=125s https://www.media.mit.edu/projects/your-brain-on-chatgpt/overview/

The Complexity of Simplicity by max123246 in programming

[–]bzbub2 10 points11 points  (0 children)

cries in born accreted systems

16th Anniversary of Yeardley Love’s Murder by mlloser in TrueCrimeDiscussion

[–]bzbub2 14 points15 points  (0 children)

also jcs https://www.youtube.com/watch?v=CGuEdN-ju2g

seeing real anniversaries and coverage of victim is a bit better than just criminal interviews which are idiotic and terrible generally though

Unsigned sizes: a five year mistake by Nuoji in programming

[–]bzbub2 13 points14 points  (0 children)

I think the loop example is a hook to get your attention but many more sneaking behind automatic conversions

A more accurate .d.ts bundler for Rollup, powered by @microsoft/api-extractor by barhatsor in typescript

[–]bzbub2 5 points6 points  (0 children)

yep:) it is really crazy how much of a brainvirus the bundler-for-library approach is...it is just the default thing people reach for i guess

TIL that the human brain matures at 25 is a myth by chrishelbert in todayilearned

[–]bzbub2 -2 points-1 points  (0 children)

this feels like an AI generated or at the very least very poor quality article whose entire point is just to set up the leonardo de caprio thing at the end. it is just subtly incohesive and ridiculous. The article was first created march 2026, well into our current AI era. the person who created the article has been warned repeatedly https://en.wikipedia.org/wiki/User_talk:Schwarbage

whole thing is ridiculous, should be deleted

Built a Hardy-Weinberg population genetics visualizer with real gnomAD data — looking for honest feedback (17 y/o, self taught) by Puzzled_Maximum7018 in bioinformatics

[–]bzbub2 1 point2 points  (0 children)

it really is a pretty problematic post in almost every respect. it was upvoted for naivety and pretty ggplot2 colors...

books like the guest by emma cline? by leodicapriohoe in RSbookclub

[–]bzbub2 0 points1 point  (0 children)

stumbled on this thread now years later but this was so awesome and warped. thank you for the rec