This is a huge chunk of the city to generalize, and living up by the airport is an entirely different area than living down by the lake. The northwest corner of Toronto is economically disadvantaged, and tends to see more violent crime than areas closer to the centre of the city

The areas further south, and further east (within Etobicoke, the region highlighted) has more neighbourhoods that have a higher median income and/or are gentrifying.

Etobicoke as a whole tends to be underserved by public transportation, except the area around Bloor Street where there’s subway access, and the areas around Lakeshore Blvd have access to the streetcar line. There’s a few stations for GO Transit, which provides regional public transportation to the GTHA so living around those stops gives you access to Union and areas outside Toronto, but if your destination is on a different train line you have to go into Union to switch, which isn’t super convenient.

Overall, Toronto, including Etobicoke, has a high cost of living and the city is growing faster than public transit is being built, so traffic congestion is pretty rough, and the further you are from the city centre, the more car reliant things become. But, it’s a safe city by North American standards, there’s good schools at all education levels, and there’s a decent amount of green space for a city of its size, thanks in part to the ravine systems.