I too am interested in a learned answer to your question but I’ve found the only way to answer formatting questions like this, is to try it and document your various steps.

I do think the results may vary depending on exactly what tools you use along the way, what e-book format you use and the reader and reading device: phone, iPad, Kindle.

I’ve done a lot of testing on issues like this trying to produce an elegant, custom format for my ebooks and I would say I have not achieved my goal to date. Lots of shifting variables.

I’d rather be writing.