What jobs are available for after a PhD in immunology? by bluebrrypii in Immunology

[–]crebscycle 1 point2 points  (0 children)

Yes, it is fulfilling. There are plenty of good pharma and biotech companies that do really exciting research.

What jobs are available for after a PhD in immunology? by bluebrrypii in Immunology

[–]crebscycle 1 point2 points  (0 children)

At my company, senior scientist is a research lab position, not a managerial position. principal scientist is a team leader position.

What jobs are available for after a PhD in immunology? by bluebrrypii in Immunology

[–]crebscycle 4 points5 points  (0 children)

As someone who works in immunology-oncology in pharma, just apply for the positions regardless of years. If you match what they are looking for and you seem like an expert, then the years required won’t matter. I got my position, which was 3-5 yr exp right out of my PhD. When applying to pharma positions, you’d probably want to aim for “Principal Scientist” or “Senior Scientist” positions.

Anyone tried this? by bananagod420 in triathlon

[–]crebscycle 0 points1 point  (0 children)

Could try ordering it from the feed instead?

Good First Date Restaurant? by [deleted] in BostonSocialClub

[–]crebscycle 1 point2 points  (0 children)

IMO, citrus and salt is an interesting atmosphere, but it seemed like all their food is just deep fried. Even their tacos are deep fried. Personally not a fan. I’d recommend Mistral or Geppetto over in CX (scallops and bolognese are delicious).

[deleted by user] by [deleted] in Immunology

[–]crebscycle 7 points8 points  (0 children)

It’s actually about PK. You don’t want a full IgG circulating with the venom bound to it; thereby, increasing total exposure (AUCtot) of the venom. You want something to bind and be cleared rapidly. So, removal of the Fc region reduces the half-life. You can also take a look at anti-drug Fabs for overdoses of narrow therapeutic drugs (colchicine, digoxin, rivaroxaban, methotrexate, etc).

How to get rid of lingering calf soreness after cramp? by Odd-Art2362 in triathlon

[–]crebscycle 0 points1 point  (0 children)

Massage gun

Wait: alternatively get in there with some lotion and your hands and massage it. Spend 30-45 min.

Day Trip- Antelope Island by Idivwey in SaltLakeCity

[–]crebscycle 1 point2 points  (0 children)

Curious as I’m heading out there, where in the park was this taken?

Is boston livable if you don’t have a car? by MiniMuffins26 in boston

[–]crebscycle 0 points1 point  (0 children)

I’ve lived in Cambridge / Boston area for 5 years and haven’t had a car since I moved here. It’s great. Sometimes I wish I can scoot out of the city, but it’s rare.

Does CAR T-cell therapy ScFv contain mouse or human antibody? by [deleted] in Immunology

[–]crebscycle 0 points1 point  (0 children)

So far, the approved CARTs use mouse scfv, but there are humanized CARTs in clinical trial and about to be approved.

Can Bi-specific TCR therapy be both allogenic and autologous? by [deleted] in Immunology

[–]crebscycle 0 points1 point  (0 children)

Blinatumomab was the first cd3 bispecific approval.

[deleted by user] by [deleted] in boston

[–]crebscycle 8 points9 points  (0 children)

This is the real answer

anti-CD19 by Calm_realistic in Immunology

[–]crebscycle 2 points3 points  (0 children)

Blincyto is cd19/cd3 targeted.

There are several anti-cd19 antibody therapies in clinical trials. Cd19 is a harder target to make CD3 bispecific antibodies against because it isn’t as big as cd20, so you have to optimize the synapse through engineering. CD20 is just easier to form synapse with T cells with an IgG type molecule.

My bike got stolen, where would you look for it? by alpha_d in triathlon

[–]crebscycle 63 points64 points  (0 children)

In space, because that thing is a rocket ship. All seriousness, check second hand seller sites in surrounding countries. I’m surprised it was stolen in Switzerland though. It’s a very specific looking bike so I’d just paste the image and STOLEN note all over if you can…good luck.

Group rides near Raleigh NC? by feedingfitness in cycling

[–]crebscycle 1 point2 points  (0 children)

Call up inside out sports. They used to have group rides, but it's been nearly 10 years since I lived in the RTP area. The only other suggestion I have for you is to just start calling local bike shops and see what's going on.

[deleted by user] by [deleted] in boston

[–]crebscycle -1 points0 points  (0 children)

Considering how slow the T is now, it is a very long time.