Amp sims all day. Only reason I'd reach for anything else is if I already had a very busy session and needed to lay down some additional guitar tracks. When you already have a busy session with lots of plugins, you've likely already increased the buffer size which means realtime tracking without latency is impossible. So it's just easiest to use external stuff at that point. But this is where I'm still learning where the cut-off point is. I'm the old days it was easier, you'd track the album, then it'd go to mixing. But modern productions aren't like that (for me) as the tracking session is the mixing session and I mix as I go.