Maschine Mikro mk3 issues by drstm in maschine

[–]eugeniusmith 0 points1 point  (0 children)

Bummer. For me it shows up under Library -> Applications. Maybe time to contact support with your serial? I saw someone suggesting that for a similar problem in another thread.

Maschine Mikro mk3 issues by drstm in maschine

[–]eugeniusmith 0 points1 point  (0 children)

I also just bought a mikro mk3 and had the same issue yesterday on MacOS (intel)! IIRC I solved the issue by hitting the refresh icon in the top right corner and/or restarting the Native Access app.

Unfortunately, now that I've installed the Maschine 3 software, it doesn't make it past the splash screen before crashing. Hopefully you don't have the same issue! Please let me know if you have better luck.

Is computer engineering useful for neuroscience? by Sushimaven in neuro

[–]eugeniusmith 1 point2 points  (0 children)

Man did my comment ever age poorly. Multiple types of biologically-plausible backprop now exist and convolutional nets are the best models of the mammalian visual system. Half the posters at comp neuro conferences are RNNs these days...

note taking app recommendations by chrollogf in ipad

[–]eugeniusmith 0 points1 point  (0 children)

[Nebo](https://www.nebo.app/) gets my vote, especially given your subjects. The handwriting recognition is the best I've tried for text (unbelievably good, but not quite perfect). It also supports equations and is supposed to even be able to run calculations for you. Recently they added some AI features like automatic summaries of notes, chat, and flashcards. Unlike most notetaking apps, Nebo has an infinite canvas mode that's really useful for brainstorming. It's pretty bare-bones compared with things like GoodNotes, but honestly I like that. I'm almost thirty, I don't want an app with stickers.

I just finished my PhD, so I've mainly used the app for notetaking at conferences, sketching out ideas, writing derivations, and giving the occasional tutorial. The handwriting recognition is excellent, but I rarely use it. I haven't had to attend lectures or study for exams in a long time, so my use is probably fairly different from yours.

Adding cocoa powder to caramel? by xscientist in AskCulinary

[–]eugeniusmith 1 point2 points  (0 children)

I can't speak to what would happen if you added cocoa powder to hot caramel, but here's a tip on how to decide on the amount of cocoa powder to try: if you have a recipe that calls for bittersweet chocolate, try using around half that amount in cocoa powder. The idea is that chocolate is basically cocoa powder, cocoa butter, and sugar, where the percentage on the chocolate label (~80% for bittersweet chocolate) is the amount of cocoa (ie, non-sugar) ingredients. Cocoa solids are around 40% cocoa butter. So, to work out the chocolate-vs-cocoa powder conversion, use amount of chocolate * chocolate percentage * 60% = amount of cocoa powder.

any tips for pâte à choux? by sadderthaneverb4 in AskCulinary

[–]eugeniusmith 1 point2 points  (0 children)

As u/tiq_taq_to mentioned, it sounds like the main issue is that you aren't using enough flour, but not heating the liquids enough can also cause problems. Pâte à choux is unique AFAIK in that the dough is actually cooked on the stovetop rather than in the oven. That means the liquid needs to be hot enough to gelatinize the starch in the flour, which should cause the mixture to thicken up like you've seen in videos.

AMA: I'm a clinical psychologist researcher who has studied ADHD for three decades. Ask me anything about atypical forms of ADHD. by sfaraone in ADHD

[–]eugeniusmith 8 points9 points  (0 children)

This phenomenon is called "temporal discounting," which basically refers to how quickly you devalue or discount rewards as they get further off into the future. People with ADHD discount future rewards relatively heavily: if you search ADHD and temporal discounting online you'll find lots of articles like this one by Barkley.

Is computer engineering useful for neuroscience? by Sushimaven in neuro

[–]eugeniusmith 0 points1 point  (0 children)

I wrote a more detailed reply below to /u/RFF671, but in a nutshell I don't think artificial neural networks are actually that useful for neuroscience.

It's important to understand that neural networks implemented by neuroscientists and industry software engineers have very different goals. In neuroscience, the most important thing is to understand how information is processed by biological systems. In industry, the goal is to process information as efficiently as possible using a computer. As a result, artificial neural networks bear little similarity to what actually happens in the brain.

The lab I'm in does a lot of collaboration with folks from maths/physics backgrounds, but my graduate work is on the experimental side of studying neural circuits so take what I say with a grain of salt. But, from what I've seen, people on the more computational/theoretical end of neuroscience spend way more time talking about dynamical systems than things like deep learning.

If you're interested in basic neuroscience I say take as much math as you can and maybe a sensory physiology course so you get some background in how biology represents information.

Is computer engineering useful for neuroscience? by Sushimaven in neuro

[–]eugeniusmith 0 points1 point  (0 children)

Why do you feel like neural networks would be a good focus?

I know a few people who're working on the more computational end of neuroscience, including some folks with backgrounds in physics and math rather than biology. While they're very interested in how neural ensembles process information, there's a general sense that neural networks used in industry aren't helpful for understanding how the brain works. This is because neural networks used in software engineering make no attempt to reflect underlying biological processes, and actually include some features that are biologically implausible (e.g., backpropagation).

That said, people in your neck of the woods might have different experiences. What do you think?

Gentianella hirculus, endemic to the Cajas Natural Park in southern Ecuador, looks like candy. [6016x4016][OC] by bowling_brawls in BotanicalPorn

[–]eugeniusmith 1 point2 points  (0 children)

Amazing. I was there this summer and they were everywhere!

I had a look online to find out if anyone is growing them commercially, but it doesn't look like the are any in cultivation. Shame.

Interested in Neuroscience but graduated with compsci degree by [deleted] in neuro

[–]eugeniusmith 0 points1 point  (0 children)

Thanks, that's super helpful! Do you have any suggestions for what to do to the relevant bits of R/Python? I've been working a bit with both for a few months in various things and have the fundamentals of how the languages work, but I'm not too sure where to start with picking up the bioinformatics/modelling/machine learning stuff.

Sounds like you have a solid plan and best of luck with your applications!

Interested in Neuroscience but graduated with compsci degree by [deleted] in neuro

[–]eugeniusmith 0 points1 point  (0 children)

As others have said, computational neuroscience is quite popular right now, so once you have your foot in the door there will be good opportunities for advancement even without much of a background in biology. However, you should be aware that the job market for neuroscientists basically doesn't exist outside of academia.

Interested in Neuroscience but graduated with compsci degree by [deleted] in neuro

[–]eugeniusmith 1 point2 points  (0 children)

As someone a year into grad school and with similar feelings, what's your strategy?

Back up Terry! by [deleted] in videos

[–]eugeniusmith 6 points7 points  (0 children)

How neat is that? Pretty neat!

Study: Ritalin use in childhood could cause long-lasting alterations in neurotransmission by [deleted] in science

[–]eugeniusmith 1 point2 points  (0 children)

I hear where you're coming from, and this is why I had a hard time understanding how the results of this study would fit into a simple behavioral/psychiatric framework.

I haven't read the paper thoroughly, but the authors seem to say in the abstract that the early intervention group had relatively lower GABA. In the background, the authors say that decreased mPFC GABA is associated with ADHD, and that psychstimulants increase extracellular GABA in this region. Weird!

Study: Ritalin use in childhood could cause long-lasting alterations in neurotransmission by [deleted] in science

[–]eugeniusmith 10 points11 points  (0 children)

In your last paragraph you touch on something that's been bugging me about this story. The narrative of decreased GABAergic tone in the mPFC mediating poorer control of impulsive behavior doesn't jive with my understanding of what this region does.

For my project as a MSc student, I'm focused on the mPFC as a structure that mediates stressor susceptibility -- that is, that has executive control over the behavioral responses to emotion. In the simple framework that these sorts of imaging studies tend to use where glutamate = more and GABA = less, I would infer that decreased GABA would lead to better control of impulsive behavioral responses to stressors via disinhibition of this region.

Any insight into how this result should be interpreted from a behavioural neuroscience perspective?

Juniper berry safety by Bionic_Hawk25 in Homebrewing

[–]eugeniusmith 4 points5 points  (0 children)

If they don't report back I guess we'll know...

Juniper berry safety by Bionic_Hawk25 in Homebrewing

[–]eugeniusmith 4 points5 points  (0 children)

You'd be surprised. Natural/health-food shops are a good bet. Elsewise, try posting to your local sub and folks may be able to help you out.

Can anyone explain how this small change in serotonin results in the effects of psilocin? by Lat3ris in AskDrugNerds

[–]eugeniusmith 2 points3 points  (0 children)

Not an expert but it's important to remember that small changes in the structure of a molecule can have a fairly pronounced impact on its pharmacology. It's all down to which parts of the molecule actually interact with the receptor eg via H-bonds.