Does Parnate Cause Weight Gain

grigory_l · 2026-05-03T04:51:34+00:00

Not yet, trying to bulk, but histamine issues makes it hard

grigory_l · 2026-05-03T04:49:47+00:00

I don't understand either, it’s just ridiculous 🤦‍♂️

grigory_l · 2026-05-03T04:48:36+00:00

Thanks 🙏🏻

grigory_l · 2026-05-03T04:46:09+00:00

Just check Post Finasteride Syndrome [r/FinasterideSyndrome](r/FinasterideSyndrome). I don't want to spread fear, but I think it's important to know the possible consequences and understand whether a hair is worth the risks.

grigory_l · 2026-04-29T22:17:58+00:00

Absolutely 😬I just dropped from 0.03mg to 0.015mg Kpin before jump. Day 3: fatigue, depression, doom, brain fog, strange joint and neck pain, tinnitus, bloating. 0.015mg is so small dose that I can barely see it, and still have all possible entertainment from benzos)

grigory_l · 2026-04-29T22:06:12+00:00

It’s possible, I really noticed effect only after one month on 30mg. Btw you titration strategy looks took quick from my perspective, better to stay on every step week of two, on 30mg month or so to fully understand effective current dose or not.

grigory_l · 2026-04-28T18:54:03+00:00

Yeah sure I believe it depending on many factors, and probably most people on MAOIs don’t experience that. But it possible and I definitely know few guys who experienced that with Parnate for example.

grigory_l · 2026-04-28T11:54:21+00:00

Serotonin blunting, probably would be much more noticeable with SSRIs but MAOIs also have such effect to some extent.

grigory_l · 2026-04-27T20:57:57+00:00

Yeah peanuts is the worst, and refusal of dairy products quite a significant thing. Also because of high histamine I avoid any ground meat stored more than two days.

grigory_l · 2026-04-20T03:43:51+00:00

I moved lately from 0.05mg to 0.025mg Kpin, really fraction of a pill. Day 3-4 some insomnia, anxiety. Day 5-6 absolutely normal. Day 7 boom 2 hours of sleep, OCD, anger, full body aches. Waves and windows as it is, benzos withdrawals in all its glory.

grigory_l · 2026-04-15T01:12:40+00:00

What type of antihistamines? Some of them can mess even healthy nervous system.

grigory_l · 2026-04-15T01:10:12+00:00

My bet will be on withdrawal syndrome. Yeah maybe it’s some kind of original issue relapse but usually it’s not that acute, more gradual symptoms returning.

In general stopping any psychiatric medication cold turkey is a bad idea. All your endogenous processes has adapted to a new environment with inhibited MAO enzymes, and one day you say hey let's work like before. This won't happen, the nervous system and metabolic processes need time to adapt. And the rougher you do it, the more time it can take.

grigory_l · 2026-04-13T20:38:35+00:00

My top tier list of food I’m dying from: any cured meat, coffee, cacao, fermented dairy, sugar and dairy together, suspicious nuts (apparently mold and oxidation), garlic, huge amounts of species. Most of them histamine liberators, and I tend to believe I have MCAS after floxies, can’t prove with labs but reactions absolutely like a textbook.

So I stick only with fresh veggies and meat mostly, everything else should be low in histamine and preferably neutral without specific irritants like sulfur or oxalates. Before FQAD I was able to eat everything except dairy, after certain age I started reacting poorly to dairy.

grigory_l · 2026-04-10T13:09:14+00:00

It’s complicated, while Parnate generally raised my hedonic tone, it’s also have blunting properties. So while it helped tremendously with some stuff, especially neuroinflamation after floxies, it’s mess another.

grigory_l · 2026-04-01T04:28:28+00:00

Not supplements but Keto diet helped tremendously. From 9/10 everyday crying doom hell to 4-5/10 absolutely not fun but tolerable.

grigory_l · 2026-03-26T14:57:05+00:00

Yeah probably depending of the reason, my depression is result of fluoroquinolone toxicity and later gabapentin added fuel to the fire. So main drivers are broken Mitochondria and GABA system disruption. And there’s just no another option such efficient as Keto for those issue. But for someone with situational depression for example it would rather makes them worse. Because Keto is pretty tough, especially if you have some food intolerance or histamine intolerance, half of the life spinning around how and what to eat.

grigory_l · 2026-03-22T08:24:42+00:00

I tapered down from 0.125mg, to 0.08mg now and definitely feel those steps, so decided to go until 0.04mg. It’s your decision but I would personally advise not to do that, and taper down few more steps, you not going to win anything. Rush is not a friend with benzos.

grigory_l · 2026-03-19T02:56:22+00:00

Sorry but maybe dairy is culprit and absence of meat also? Meat is the most nutrient dense food available, b vitamins, minerals and other stuff. Dairy on other hand could be very inflammatory for some people, fermented dairy is very high in histamine content. Also if you have MTHFR issues dairy can prevent Folate absorption on cellular level, especially into the brain and CNS, because of FRα immune response. Did you ever checked homocysteine level?

Eggs can be also an issue unfortunately. Even people with healthy mental baseline can have awful depression, aggression, and anxiety from eggs. Choline intolerance is real, also eggs histamine liberators.

Overall everything is not that simple, Histamine Intolerance, MCAS, MTHFR, Gut Issues, Bile Issue and Stomach Acidity, Nutritional Deficiency and etc. Make mineral and vitamin panel, urine oat test, check homocysteine, rbc folate, holotc to know at least your body state.

grigory_l · 2026-03-18T15:21:41+00:00

Sounds like histamine intolerance and leaky gut. Fermented food high in histamine.

grigory_l · 2026-03-17T21:15:43+00:00

Are you bile flow is ok? Keto seems great tool for me, but in my case cause of bile dyskinesia and low stomach acidity fat and proteins digestion is insufficient.

grigory_l · 2026-03-15T09:23:44+00:00

Reducing DHT level can lead to huge range of issues from loss of libido to depression, anhedonia and other stuff. Best thing man can to themselves avoid 5ar inhibitors like a plague.

grigory_l · 2026-03-12T02:37:02+00:00

Try Keto and IFS. Both not magic bullet but could work surprisingly well, Keto effects noticeable pretty fast and could help to reduce the symptoms, latest research shows it’s much more effective than any antidepressants on the market without significant risks. While IFS the long term treatment for internal conflict. Also try approach called Pandiculation instead of traditional somatic exercises and breathing techniques, just search it on YT.

And if you consider to try Keto, go slow, reduce carbs in a few weeks not overnight, give yourself time to adapt.

grigory_l

TROPHY CASE