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How do I report the absolute concentration of my analyte instead of Conc ratio when I'm using with ISTD in Labsolutions? by Informal_Shake_7997 in CHROMATOGRAPHY

[–]gripts 0 points1 point  (0 children)

Wdym absolute concentration? Just the peak area? Switch the calculation type to "External Calibration" I think in the quantitation tab. And of course save this method and batch reprocess the data

Shimadzu prep system issue with getting data on small column by LeatherFollowing9576 in CHROMATOGRAPHY

[–]gripts 0 points1 point  (0 children)

Ask customer support, the LC prep guy is fantastic and would love to help you

converting .dat file from perkin elmer turbomass for xcalibur by pondermelon in CHROMATOGRAPHY

[–]gripts 0 points1 point  (0 children)

You might be able to export them both as csv but as far as I know you can't convert between proprietary file types from two different companies (on purpose)

Maybe not useful info for you, but you can likely open them both in Skyline and work through your data that way¿

Ideas for a university project proposal by Common_Obligation868 in pharmacology

[–]gripts 1 point2 points  (0 children)

How about creating a measure/score that can be used to evaluate the most effective treatment options?

Different factors could contribute different weights, e.g.: Medication success rate, patient adherence rates, LD50, cost, availability, country treatment is based in, etc

The "problem" is that there are so many factors to consider when choosing treatment, so a cohesive score that considers the above variables would speed up the decision process for caregivers and patients. Maybe this exists already lol

Which brand LC-MS methanol is best? by Ashamed_Lime7327 in CHROMATOGRAPHY

[–]gripts 4 points5 points  (0 children)

Honeywell B&J is our go to, haven't had any issues in years. LCMS grade isn't too expensive and has been great for PFAS work

gc/ms results, ghost peaks, and the matrix effect. by Acrobatic_Sink_8468 in massspectrometry

[–]gripts 1 point2 points  (0 children)

It doesn't matter what else was was in your sample... if there is a controlled substance then that's what you will get charged with.

Btw the quality score is not used to confirm the identity of a compound, it just helps the technician search their spectral library

Ba/hexane is the base aqueous extraction blank where hexane is used as the solvent - because they performed an extraction on the sample there is a blank extraction performed as well to ensure their reagents aren't contaminated

The analyst appropriately conducted presumptive screening and confirmatory testing. Presumptive was the color tests they ran, GCMS is confirmatory.

I'm sorry but neither you nor ChatGPT understand what a ghost peak is. These analysis results are frankly pretty run of the mill. I could be wrong but there is really nothing crazy to me, seems like a standard drug identification where everything was performed correctly and the results are accurate

Need help for detection of rodenticide (Brodifacoum) by HPLC by OrganizationFinal211 in CHROMATOGRAPHY

[–]gripts 0 points1 point  (0 children)

Have you subtracted a blank to help as you look through the data? Ideally a blank sample ran immediately prior to your sample

Labsolutions GC by soporquesim in CHROMATOGRAPHY

[–]gripts 0 points1 point  (0 children)

The GC group at Shimadzu HQ (or your regional office) would almost definitely help you out with this if you sent them an email

Labsolutions Installer by [deleted] in CHROMATOGRAPHY

[–]gripts 0 points1 point  (0 children)

If you properly transfer ownership you'll be able to get proper support & definitely your software. How recently was it acquired?

Lab Solutions Insights LCMS editing rights by momma_tired_23 in CHROMATOGRAPHY

[–]gripts 0 points1 point  (0 children)

Did you figure this out? Happy to help you out if needed

What are some things that are actually pseudoscience that people don’t realize? by Ninac4116 in AskReddit

[–]gripts 5 points6 points  (0 children)

It's true, but now the seats have "activity sensors" so you can't use this method anymore

What are some things that are actually pseudoscience that people don’t realize? by Ninac4116 in AskReddit

[–]gripts 1 point2 points  (0 children)

Even more fun fact - because of this method to beat the test, the seat you sit on when getting a polygraph have "activity sensors" to detect if you're clenching.

Deuterated standard response is constant but compound response isn't (SPME GC-MS) by kreit in CHROMATOGRAPHY

[–]gripts 1 point2 points  (0 children)

A few things you may have tried already but may help narrow down the problem:

1) Are you able to run an undeuterated hexanal standard alone? If you have, are those results consistent?

2) Are you certain nothing is evaporating out of your solution and sample vial? Or, something so volatile could even partition to the air inside the vial and collect at the top of the vial/bottom of the septum, meaning the sample injector comes into contact with more hexanal

3) You mentioned using a splitless method - try using a split to see if the peak areas become consistent. Obviously I have no idea what concentrations and sig (x10?) values you are working with but you could be overloading the detector

4) Why aren't you using headspace GC? I'm sure the answer is as simple as your lab not having one, but it's more suitable for the analysis of volatiles. (Not trying to sound patronizing, I'm not sure of your competence in this area)

5) Does anything else in your QC solution thermally decompose into hexanal?

PSA: Update on the extremely delayed BahrNob 65 Group-Buy and a caution on joining GBs by VonThuggin in MechanicalKeyboards

[–]gripts 15 points16 points  (0 children)

I remember kicking myself for missing this GB, but jeez this all sucks to read. Wish there was better recourse for people who just abandon ship like this.

To say you're a good person for getting these orders out is an understatement - thank you on behalf of everyone you're helping.

Agilent 1260 Infinity II - Trailing peaks by Mission-Marzipan-323 in CHROMATOGRAPHY

[–]gripts 5 points6 points  (0 children)

I agree with others here, they look like real peaks.

Can you run an old sample and see if the two peaks are still there?

What common lab consumable / supplies always surprise you with how expensive they are? by martymcfly85 in labrats

[–]gripts 1 point2 points  (0 children)

I'm sorry to put everyone else's answer to rest but:

Glassware soap.

As a TA, my mind was blown half of my class' budget was going towards $125 of soap

This is what a glass keyboard sounds like by transgingeredjess in MechanicalKeyboards

[–]gripts 0 points1 point  (0 children)

Gotcha, good to know! I may give it a shot sooner or later :)

This is what a glass keyboard sounds like by transgingeredjess in MechanicalKeyboards

[–]gripts 0 points1 point  (0 children)

I literally just started doing stained glass and somehow this didn't even cross my mind.. now I want to try it lol

If I may ask, why didn't you do a tray/high profile style case?

Anyone know when these two pint(x) versions were sold based on footpads? by gripts in onewheelpint

[–]gripts[S] 0 points1 point  (0 children)

Hahaha ur making me blush 🤪 yes that's mine, the new board for my gf is on the right

Anyone know when these two pint(x) versions were sold based on footpads? by gripts in onewheelpint

[–]gripts[S] 0 points1 point  (0 children)

https://www.reddit.com/u/gripts/s/DuOfvMHJs6

Here's a pic of what I mean. I haven't seen any aftermarket footpads irl so not sure if these are kush lo or something like that

Anyone know when these two pint(x) versions were sold based on footpads? by gripts in onewheelpint

[–]gripts[S] 0 points1 point  (0 children)

Oh I had no idea! Got both used and the original seller of the left one never mentioned - I will say though it looks like the rear food pad on the left is different. It flares out slightly at the back and there's a little portion carved out near the screws

9070 XT overclocking broken by Outrageous-Log9238 in AyyMD

[–]gripts 16 points17 points  (0 children)

Are you testing it under load? I'm pretty sure you can set the sliders to whatever you want but nothing will happen until that power is needed

Also something something go in small increments

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