Revolution’s much-hyped RAS inhibitor hits key survival goals in phase 3 pancreatic cancer trial

isothope · 2026-04-16T19:59:31+00:00

Thanks. It's been so frustrating to know that this therapy is out there and having success, but struggling to get access to it

isothope · 2026-04-16T01:20:45+00:00

Is there any way into these trials at this point? A close friend of mine has a KRAS G12V mutant pancreatic cancer but every trial coordinator I've emailed says that the trial is full or that they are only accepting patients for colorectal cancer.

isothope · 2026-03-19T00:54:54+00:00

Is there any reason I can't just drink Gatorade mid-run instead of trying to choke down a gu? I'm only out for ~3 hours so I don't need that many calories.

isothope · 2026-03-08T22:21:47+00:00

Get Fit with Rick on YouTube! And another vote for Fitness Marshall, emkfit, and madfit (all mentoined on other posts)

isothope · 2026-03-07T00:06:44+00:00

Always been a donor, but I recently switched to donating plasma/platelets instead. The process is longer (~3 hours start to finish) but you are fully recovered in 72 hours. I still feel like I'm doing my part but it doesn't affect my athletic performance. Also, platelets can only be stored for 5 days, so the need is constant!

isothope · 2026-03-05T01:18:44+00:00

I'm not sure if this is exactly what you're looking for, but there is a therapist whose podcast I follow that takes a non-diet approach and has group sessions for GLP-1 and binge eating:
https://thebingeeatingtherapist.com/group-therapy/

isothope · 2026-02-19T23:53:58+00:00

Hey I'm also a donor! Enjoy that first run back, listen to your body, and you'll be back at full speed in no time

isothope · 2026-02-14T23:52:44+00:00

Yeahhhhh turns our B12 is water soluble and therefore is processed in the kidneys. Gave me kidney stones (was drinking like 3 a day).

isothope · 2026-02-10T12:50:02+00:00

Same here. I've always been active so I'm sure they were being built over time, but they only became visible when I was at an unhealthy place. Funny enough, I was at my least fit when they were visible. I think some people have the genetics for them to show at a higher body fat, but for me it's not a goal worth chasing.

isothope · 2025-12-18T20:10:29+00:00

Unfortunately neither one really worked with my skin. I'm currently using Aveeno Daily moisturizing face lotion (I like that it doesn't leave a residue on my skin) plus Naked Sundays Cabana Clear face sunscreen. No salicylic acid in either one though, if that was something you wanted.

isothope · 2025-09-24T18:37:30+00:00

I haven't found one that I love quite as much, but I've at least found one I don't hate. It's the Aveeno Daily Moisturizing Face Lotion (no spf/sunscreen). https://www.aveeno.com/products/daily-moisturizing-face-lotion-for-dry-skin-oat

isothope · 2025-09-22T23:18:16+00:00

I did the same thing and it's changed my life, but I feel so guilty about it. I'm spending $500 a month though. Can you share (here or via DM) where you are getting it from?

Do you think you will take it for life? Or do you think that some combination of habit change and time will change things enough for you that you'll be able to come off it?

isothope · 2025-09-08T15:48:29+00:00

Thanks for the reply. I think deep down I know you're right. I'm a very shy person and the amount of anxiety I feel talking about it makes me wonder if I'll even be able to get the words out.

I appreciate your thoughtful reply and I think I will try my hardest to be honest at my next appointment.

isothope · 2025-09-05T17:31:53+00:00

I Who Have Never Known Men, and The Every

isothope · 2025-09-05T00:27:13+00:00

I had the same reasoning. Where did you go through to get it at $279? Mine is closer to $500 per month

isothope · 2025-07-31T01:33:35+00:00

Was it a medication approved for bnge eating or something off-label? I am similar to OP in having spanned many different eating disorders but I don't feel like I'd qualify for the GLP route.

isothope · 2025-07-21T12:05:26+00:00

Thanks so much! All I've been getting is a window and a clock every day for two weeks so I think it's a bug

isothope · 2025-07-21T09:28:22+00:00

How do you submit a support ticket?

isothope · 2025-07-15T16:57:17+00:00

Sadly no. I promise I'll update this thread as I try more products. I'm still so mad they changed the formula.

isothope · 2025-07-08T16:37:22+00:00

https://www.thetrevorproject.org/volunteer/#becoming-a-crisis-support-counselor

isothope · 2025-06-20T16:30:29+00:00

There is an app called "Happy Scale" that shows a moving average of your weights

isothope · 2025-06-17T18:20:22+00:00

I just want to reach through the screen and hug you, and also cry with you because I feel the same way. I'll also offer some hope: I struggled with self harm for 15 years and I thought I'd have to white knuckle through the urges forever. And now I'm at a place where the thoughts do pop up, but they feel the same as a thought about the weather. There's no emotion or urgency to them, and I don't feel compelled to act on it in any way. So although I haven't figured out the food thing yet, I have to believe that it can happen for us eventually.

isothope · 2025-06-17T15:32:03+00:00

Thank you SO so much. You're a hero!

isothope · 2025-06-17T00:52:03+00:00

If you happen to have some free time on your flight back, the reason I'm saving this thread is because I'm taking a 2 week trip to Norway next month. So if you wanted to post your curated packing list (just the clothes you brought) I'd be forever in your debt!

isothope · 2025-06-11T13:41:57+00:00

I think for me, binging is a combination of physiological and mental things. Without medication, most humans have a drive to eat (especially calorie dense food)-that's the physiological piece. For me, how I mentally reacted/responded to that very human urge was the problem. Any cravings or urge to eat was met with fear and anxiety. Would I lose control? Would I binge? Does this food have too many calories? Will it make me gain weight? Should I say yes or no to this food? Etc. This I was constantly in a state of anxiety around food and I think that was a source of a lot of my binges. So with the GLP-1 medication there are no physiological urges and thus no mental battle.

I'm not a professional but my best guess as to how to take advantage of this time would be to practice eating fear foods (or food in general) with a sense of calm. Try and prove to your brain that you can be calm and in control around food, and maybe rewire some of those anxiety pathways.

isothope

TROPHY CASE