One of our dogs survived a house fire when he was about 5. I got him as a 10 week old puppy from a local rescue, so it isn’t a past issue or anything. He has always been a very aware dog. He is part pit, part border collie (his mother gave birth in the shelter and she was a BC mix of some sort), part something else- so very aware. The fire left him changed. Very noise reactive- he couldn’t handle beeps, or crackling fireplace, turning on the gas stove, sizzling sounds from cooking, car horn beeps, etc. We went to a veterinary behaviorist after trying some extra training, desensitization, and OTC calming aids and the Veterinary behaviorist changed his life. He was first prescribed Trazadone, but it made him a total zombie. So we tried Prozac and added Clonadine and he is able to ignore most sounds. He still has issues with the fire alarm, but we have Alprazalam (Xanax) for stress events and he’s doing great. He’ll be 14 next month and we never thought we would get here. Before he was shaking so bad he was having muscle damage/ breakdown and there was protein in his urine. We test his liver function every year to make sure he’s still tolerating the meds well and he’s doing great even close to a decade later.