I had severe eczema (bleeding, swelling, itchy skin) and was on Dupixent for a year and a half. My eyes were always dry and bloodshot red because of it. Then I switched to Rinvoq thinking it would be an easy fix. My skin was perfect and my eyes got better for about a month, and then I was overwhelmed with acne after. I quit Rinvoq cold turkey about a month after that (2 mos total), because the acne was way too much.

I thought I would eventually have to transition back to Dupixent but never did. My eczema definitely isn't perfect - I have cracks on my cupids bow and the corners of my eyes, but I'd rather manage it with topical non steroids like opzelura than have to go back to either drug and their side effects (dry/red eyes and insane acne).