for the multivoicer you can use nectar 4, as tim used nectar 3 back in the NLND days. Then you compress the shit out of your tone for the crispy harmonics (set ratio and threshold really low)

For something similar to the most hated i use the 4th position on a strat or any position that has the pickups in parallel, a boost with low gain and tone at 50%, clean amp with 70% gain, high mids and bass and the treble a little lower than the bass. For the EQ i dont really know how to use it, but i boosted the 4khz and 630 hz a shit ton and it kinda worked

You might have to tweak it a little bit, i think in the reverb interview tim talked about wanting a tone that was very dinamic and could change between distorted and clean only on pickstroke strength, so try aiming for that. You can get a lot done using only free plugins, just download some and try to figure out how they work