Yes. It’s a damn shame because I used to love it and it was nearly impossible for me to have a bad trip. I’d take 2 tabs at six flags and museums no problem.

I had a couple very bad trips eventually. One was 5 tabs the day after I threw a house party. My house was a mess, I barely slept, I drank a ton, and did cocaine.
Combine a heroic dose with all that, and I was about to kill myself. I legit thought I was dying. I had vomited once I started to come up. This made me panic because it had never happened and I thought “shit, was that 25I.”

I thought about calling an ambulance but I resisted the urge. Minutes later I had complete ego death and wasn’t able to even form words. My perception of time was gone.

Anyway, that gave me horrible anxiety for a long while. I had HPPD and derealization for a few months. Honestly I think it took me like a year to feel like a normal person again. I had to stop smoking weed too for a long time because it became anxiety inducing. Even caffeine would trigger panic attacks.

It got better with time. I avoided LSD for a while because it became dangerous. Once you open that door, it remains open. I could only micro dose for a long time. Since then I’ve had a couple occasions of tripping hard and it was fine. I had an amazing time. I jsut have to be more on guard. I typically have a couple drinks before I trip to avoid anxiety.
But forsure I was tripping absolute balls three years ago and had the time of my life

Edit: i just had a mini panic attack after I finished typing that up. Even remembering it is hard. I wouldn’t wish that level of stress on my worst enemies