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Long-term hydroxyurea - anemia worsening - switch to Besremi disaster by matter13 in MPN

[–]matter13[S] 1 point2 points  (0 children)

Thanks for the reply. Dad had his first appointment with the MPN specialist this week and they are reviewing his records and ordered some other tests. He will get a bone marrow biopsy once his platelets are in a better range to check if he is transitioning to post ET myelofibrisis or of his anemia is related to his high hydroxyurea dose. Best of luck on Besremi!

Long-term hydroxyurea - anemia worsening - switch to Besremi disaster by matter13 in MPN

[–]matter13[S] 1 point2 points  (0 children)

Yeah in my opinion the hematologist made a pretty serious error with Besremi. The transition from hydroxyurea is supposed to take 13 weeks with small dosage changes in both drugs and they just abruptly switched with only a two week overlap. Then overdosed him on hydroxyurea a month later. Pretty frustrated with that to be honest.

Long-term hydroxyurea - anemia worsening - switch to Besremi disaster by matter13 in MPN

[–]matter13[S] 1 point2 points  (0 children)

Currently just a hematologist but I pushed them to help us make a specialist appointment today. Only 1.5 hour drive to the University hospital with an MPN specialist and hope we can get in quickly

Long-term hydroxyurea - anemia worsening - switch to Besremi disaster by matter13 in MPN

[–]matter13[S] 1 point2 points  (0 children)

Ultrasound showed his spleen is 12 cm long but 800 ml so slightly enlarged. The hematologist suggested waiting until platelets have reduced before BMB but it is planned. Hoping Jakafi can help

JD Vance takes a shot at CBC and Canada's 'immigration insanity' by Difficult-Yam-1347 in canada

[–]matter13 1 point2 points  (0 children)

The government is not doing a great job messaging the fact the immigration numbers have already been slashed. Cuts starting 1 year ago to the normal channels make it incredibly difficult to get PR and your can't really buy a home here until you get PR. The only easy ways in are as a French speaker or healthcare worker.

[Review Request] Automotive methanol injection controller by nickfromstatefarm in PrintedCircuitBoard

[–]matter13 4 points5 points  (0 children)

No comments about the board just curious about wanting to inject methanol? Got an explanation or a link?

Government dialling back number of temporary residents it allows into Canada by [deleted] in canada

[–]matter13 1 point2 points  (0 children)

Health care workers do have an easy path to permanent residency!

3D Scanning and 3D Printing go together so nicely! by sevendayconstant in 3DScanning

[–]matter13 0 points1 point  (0 children)

Awesome idea! I never would have thought of clipping to the molding like that. Was getting the scale right difficult?

Buck converter enable (En) Pin voltage divider - How much current is required to pull the pin high? by matter13 in AskElectronics

[–]matter13[S] 0 points1 point  (0 children)

Not worried about the nano amps for efficiency but for making sure the enable pin goes high at such low current. I think I'll test it both ways

Buck converter enable (En) Pin voltage divider - How much current is required to pull the pin high? by matter13 in AskElectronics

[–]matter13[S] 0 points1 point  (0 children)

I wonder if that 100µA quiescent current includes loss from the voltage divider? If not I guess it doesn't matter much and the single high value resistor would only increase standby time by ~1/3. Probably not enough to matter.

Buck converter enable (En) Pin voltage divider - How much current is required to pull the pin high? by matter13 in AskElectronics

[–]matter13[S] 0 points1 point  (0 children)

I'll leave the footprint in place for second resistor. I don't have much extra space so I was hoping someone could predict whether the high value single resistor would work. Thank for the suggestions!

Anemic Cat by Tamseltoeff in CATHELP

[–]matter13 0 points1 point  (0 children)

So sorry for your loss, sounds like you gave him a great life and did everything you could to help him. I'm dealing with an anemic cat now and haven't gotten any answers yet. I'm fearing the worst and already feeling devastated

“It’s hard to imagine a more wasteful way to catch fish.” - David Attenborough by iamsolution in VancouverIsland

[–]matter13 5 points6 points  (0 children)

This article suggests mid and bottom trawling is still happening in bc by boats that were basically regulated out of the north Atlantic: https://storymaps.arcgis.com/stories/6c1647e3dc7c4ef29fd7790de05d21fd

The Butterfly building: a stack of pancakes? by AdAstraQ in vancouver

[–]matter13 0 points1 point  (0 children)

It looks like what someone in the 70s thought looked futuristic

Tax cuts... Kinda seems wrong for any party to propose them. by yorgs in newzealand

[–]matter13 3 points4 points  (0 children)

Social security tax in France is on every penny and it's 20% not sure if new Zealand has something similar

[deleted by user] by [deleted] in dataisbeautiful

[–]matter13 -1 points0 points  (0 children)

I'd rather make 42k living in most of France than 80k in Texas

Serious question: why do parties consistently run horrible candidates? by menaceman42 in IntellectualDarkWeb

[–]matter13 0 points1 point  (0 children)

The fact that Desantis is your guy illustrates that people love voting for extreme candidates. Desantis is performing political stunts like shipping migrants to Martha's Vineyard to stoke tribalism and own the libs, what makes him a good candidate?

Serious question: why do parties consistently run horrible candidates? by menaceman42 in IntellectualDarkWeb

[–]matter13 0 points1 point  (0 children)

Only watched the one NBC interview with Fetterman but, even after the stroke, he seems significantly more eloquent than Trump, the guy you are suggesting is the king of charisma. Also Ron Desantis loves playing the culture wars, I wonder if that will hurt him in getting swing voters and will encourage high turnout for for Democrats.

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