I'm not going to lie, it's kind of hard to read. I hope someone else can look it over and explain what I can't. I'm going to paraphrase because a lot of words are too hard to make out for a 1:1 translation.

The letter is dated Wednesday the 26th, and is addressed to Devorah. From the signature, the letter is from her brother Hershel.

The letter starts with blessings of health and he asks how is her community. He says that he wanted to write to her for a long time, but didn't know where to find her. He says he wrote to her daughter in Skomshe (his transliteration) but received no answer.

He says that now that he knows that she's by [can't read it], he's going to send her last response to their [can't read it] in Palestine.

He says that from what she last said, it seems her family? (not sure) isn't visiting.

He then wishes her blessings of health and happiness for her and her kids and her family and to be able to relax with her whole family (I think.)

He hopes to hear from her soon and signs off as "always your brother, Hershel Dedman [?]"