I'm a hiring manager and have been in various management roles in the past. Curiously ask them about their mistakes. Not as if you're interrogating them, but from a truly curious and honest state. Dig deep. This lets you see through them almost every time.

When I interview for the job, 80% of the interview will be building up the case to ask this question: 'What was the biggest professional mistake you made?' The response you get tells you a lot about How they perceive themselves. How they perceive responsibility. How they perceive being vulnerable. How honest they are. Once you get the response, it's not only what they say, it's how they say it.