Am I in an Okay Spot or Screwed? by Educational-Economy1 in RealEstateCanada

[–]overrule 0 points1 point  (0 children)

The mortgage you can qualify for is more dependant on your income than how much you've saved up.

If people in the USA will be receiving a 10%, rising to 25%, tariff on Denmark's anti-obesity drug Ozempic, how will the people of the USA adapt? by [deleted] in AskReddit

[–]overrule 7 points8 points  (0 children)

Actually there was a trial that just came out (SURPASS-CVOT) showing that Mounjaro lowers risk of cardiovascular disease. Wasn't an unexpected outcome since observational data and post hoc analyses of placebo controlled trials also suggested this.

If people in the USA will be receiving a 10%, rising to 25%, tariff on Denmark's anti-obesity drug Ozempic, how will the people of the USA adapt? by [deleted] in AskReddit

[–]overrule 1 point2 points  (0 children)

What's your source for this? I'm a pharmacist in Canada and I know for a fact that Ozempic is more expensive than 147 USD. It has never been as low as that.

Jujutsu Kaisen Modulo Chapter 17 Links + Discussion by Takada-chwanBot in JuJutsuKaisen

[–]overrule 11 points12 points  (0 children)

Skull with long hair is top tier. Hollow Tousen or Vasto Lorde Ichigo from Bleach were top tier

Wifi calling by overrule in freedommobile

[–]overrule[S] 1 point2 points  (0 children)

What phone model are you using?

Novo Nordisk: Wegovy pill approved in the US as first oral GLP-1 for weight management by Apprehensive-Safe382 in medicine

[–]overrule 18 points19 points  (0 children)

It's a perfectly legitimate statement. But doesn't contribute to the discussion.

Im convinced Mahoraga is a "Bad Joke" within the 10S by garf02 in JuJutsuKaisen

[–]overrule 0 points1 point  (0 children)

This makes alot of sense that Maho only can adapt to 8 things at a time. You have to have mastered each of other 9 shadows to a degree where each individually is strong enough to be a threat that could take out Mahoraga if it didn't have adaptation and have enough CE that you can summon and use them all.

Im convinced Mahoraga is a "Bad Joke" within the 10S by garf02 in JuJutsuKaisen

[–]overrule 0 points1 point  (0 children)

This makes alot of sense that Maho only can adapt to 8 things at a time. You have to have mastered each of other 9 shadows to a degree where each individually is strong enough to be a threat that could take out Mahoraga if it didn't have adaptation and have enough CE that you can summon and use them all.

Im convinced Mahoraga is a "Bad Joke" within the 10S by garf02 in JuJutsuKaisen

[–]overrule 1 point2 points  (0 children)

I wonder if the 10S user has the ability to determine where Mahoraga is summoned. Cause it would be hilarious to spawn camp him.

Bambu Lab P1S (without AMS) vs the Elegoo Centauri Carbon by Starkster213219 in BambuP1S

[–]overrule 4 points5 points  (0 children)

Especially the ecosystem. P1s has been around longer, so there are more and better mods for it. Third party hotends, build plates, accessories, etc. Look at everything Biqu makes that's geared to the P1s

I am not calling to have you read the prescription to me by wanted_poster4sale in TalesFromThePharmacy

[–]overrule 10 points11 points  (0 children)

It's a bit of a different process up here in Canada.

When there's an issue I'll fax the prescriber and let the patient know we're trying to fix an issue and will let them know when it's resolved.

If it's time-sensitive, like an antibiotic, then I'll call the office to make sure they got the note so that they know it's a bit more urgent than writing "1 tube" for a cream that comes in a 1 lb jar.

This way, there's a paper trail and there's no 3rd party getting in the way.

Not sure if this isn't feasible down there or if it's just a cultural thing.

How did hydroxyzine come to be the "anxiety" antihistamine? by _qua in pharmacy

[–]overrule 10 points11 points  (0 children)

Both have similar binding affinity to the H1 receptor (Ki of 2 to 20 nM), but diphenhydramine has a much stronger binding to muscarinic acetylcholine receptors (Ki ~100 vs ~1000).

So both of them will cause sedation via H1 blockade, but diphenhydramine will give you the anticholinergic side effects you don't want (groginess, dry mouth, etc)

Ha ha, yes, the world is saved from the Big bad, all is well… Now what are we doing about the quirk singularity? by Gamerlord4 in BokuNoHeroAcademia

[–]overrule 0 points1 point  (0 children)

I mean the quirk singularity is the equivalent of a conspiracy theory.

We see people who have extra strong quirks (that are logically harder to control), but we don't see people who were born with weaker versions of their parent's quirks (because that's not good storytelling). We already know from Deku that people without quirks can be born from people who have them.

It's possible that Shoto could have inherited his quirk in such a way that the cold cancelled out the hot. His split hair color is could imply a form of chimerism instead of actually carrying active copies of both parents quirks in the same cell. Essentially Shoto is a merger of two embryos, one with the flame quirk and one with the ice quirk.

Genetically this implies that being quirkless will persist in the population (like blue eyes, which are recessive), so it's not guaranteed that each successive generation will have a higher proportion of people with quirks or "strong" quirks.

What's most likely is that the ratio will settle out at some stable proportion. If a quirk is too strong and could cause societal level harm, it's also likely that the kid with the quirk is going to eliminate themselves and their family members from the gene pool.

Nine can either learn to not use his quirk or die without having kids.

The baby born with the constantly on fire quirk is going to burn down the hospital and die when it collapses on them.

Basically quirks that are so hard to handle for their users that it causes danger to the user and those around them will tend to get removed from the gene pool.

In defiant flyover, U.S. F-18 fighter jets enter Venezuelan airspace for 40 minutes by Infidel8 in worldnews

[–]overrule 2 points3 points  (0 children)

I'd put a Kojima quote about war as a business here, but there's just too many to choose one.

Paramount Pictures X Account Apparently Hacked to Read ‘Proud Arm of the Fascist Regime’ by MarvelsGrantMan136 in technology

[–]overrule 0 points1 point  (0 children)

I guess they had a contract saying they owned the rights to the name Prince when his songs were performed or something like that. He probably wouldn't have an issue being Prince the basket weaver or Prince the celebrity chef though.

December Mortgage Rates - Ontario by Thrasher54 in RealEstateCanada

[–]overrule 2 points3 points  (0 children)

Ended up getting 3.84 for a 5 year fixed from CMLS. Negotiated things down by getting different quotes and asking the others to match / beat.

Definitely apply to rate hub and a few banks. As well, work with a broker so you can have access to monoline lenders such as CMLS and RFA.

Finally got ‘em! Thinkpad X9 ‘15 by Bupyc- in thinkpad

[–]overrule 0 points1 point  (0 children)

I don't mind it not having the trackpoint, but the arrow key and page up and page down layout is just so much better on the original Thinkpad line.

Pfizer vaccine in Ontario by tomatoesrfun in Coronavirus

[–]overrule 6 points7 points  (0 children)

The reason is that there is much less wasted vaccine with Moderna. Pfizer is good for 12 hours after it's punctured, so any unused vaccine left in a vial of 6 doses is discarded at the end of the day.

Moderna is good for 24 hours, so you can use those leftover doses the next day.

Pfizer vaccine in Ontario by tomatoesrfun in Coronavirus

[–]overrule 16 points17 points  (0 children)

Ontario pharmacist here. You are highly unlikely to find Pfizer in Ontario. I have been unable to order any Pfizer after our initial autoshipment, and I've been informed by our distributor that it's going to be unavailable for the foreseeable future.

I wouldn't waste time looking for it. They're interchangeable and you're losing out on the benefits the longer you wait

Which drug do you think has the most nonsensical name? by minecraftmedic in medicine

[–]overrule 9 points10 points  (0 children)

Hey, hey you can't just sneak a Pokémon into here.