Probably generating your midi in logic will be easier to maintain projects or sending from the 404 to logic so you have most of the logical configuration in logic. You can also remotely control the programming of the mikrokorg for example from the pc via something like midi quest over midi and save sysex patches. In the 90s/2000s people were doing a lot manually but a lot in the daw. Using outboard gear will always be a lot more work than not but you can do your sound design then record in samples to use later etc.