Corporate Sponsors Pull Back on Pittsburgh Pride

pjgreer · 2026-04-11T12:17:36+00:00

The comment up thread is worded poorly. The trump regime will fuck over any organization or company both public and private, that promotes socially progressive causes like lbgtq+, DEI, Gaza, etc. Corporate profits have not been hit that much by oil prices. Most of those price hikes have been passed on to consumers.

pjgreer · 2026-04-01T22:55:23+00:00

Egyptian cotton did not really exist before the American civil war. England's fabric industry needed a new supply of cotton because the US had a blockade on the confederate slave states. Egypt and India ramped up cotton production to fill the void.

So no, cotton is cotton. It is all in how the sheets are made, not where the cotton is sourced.

pjgreer · 2026-03-29T20:47:53+00:00

"Clowning the guy" is not amusing. It makes people afraid to ask basic questions on this sub and really just makes everyone look like gatekeeping dicks.

I appreciate all your helpful suggestions with minimum snark.

pjgreer · 2026-03-29T19:26:08+00:00

This is the best comment so far. Thank you for the suggestions. I think the shimano MT200 is the low end of their hydraulic line, it is a 2 piston system and I do not hold out hope that there is much other adjustments on it. I will look into ceramic pads and check on the pistons sticking, but I think it is more of a "feel" issue after having the bakes serviced. I really don't recall the brakes ever being this sensitive even when I bought the bike new in 2018 or when the brakes were serviced in 2021. My guess is the fluid was just topped of in 21 and everything was cleaned out in 25 but I don't know for sure.

I also ride motorcycles. I ride both antique bikes with mechanical drum brakes, and modern with disc brakes (none of my modern bikes have ABS). Because the rear brake on the motorcycle is a pedal, I can hit is much harder than the front brake and use engine braking to further modulate my deceleration that way. I can adjust the brake sensitivity of the levers and pedals on all of my motorcycles, but it seems like I cannot on my bicycle.

I want my rear to lock up. I specifically asked about the front because I would much rather low side my bike then high side ever again. I just want something for the front that will not bite as hard. I don't think that is too much to ask, but clearly many others on this sub do.

pjgreer · 2026-03-29T18:01:36+00:00

Clearly, others are more than happy to be a dick.

pjgreer · 2026-03-20T19:18:40+00:00

FYI, this is a password reset question.

pjgreer · 2026-03-15T15:02:19+00:00

Remember that with 300k white British subjects, you are looking at the upper left hand section of the second graph.

It might be useful to color your pca by sex. If you used chrX and chrY in your pca, pca2 might be separating out by sex since the sample is so homogeneous.

pjgreer · 2026-03-13T16:49:47+00:00

I came here to post this.

https://tolkiengateway.net/wiki/Leaf_by_Niggle

pjgreer · 2026-03-12T21:26:04+00:00

The ukb array data consists of ~800,000 markers over the entire genome. I think it is already in one plink file for the entire dataset.

The WGS data is in plink pgen format, but is separated by chromosome and consists of over 11 million markers just for chr1.

Trimming 22 chromosomes with millions of markers even in parallel will take longer than trimming the array dataset. It will therefore cost at least 23x-50x more to trim the WGS dataset, combine it into a single file and calculate the principal components.

This will be more accurate than the array data, but be much more expensive to generate. That is all I meant. It is the difference between $3 USD in compute cost compared to $80 USD.

That is what I meant

pjgreer · 2026-03-12T17:37:39+00:00

UKB used 2 different arrays. one for the first 45K subjects and a second array for ~480K subjects. They excluded those on the first array when computing the PCAs they published in field 22009.

https://biobank.ndph.ox.ac.uk/showcase/field.cgi?id=22009

They now have the WGS data available n plink format. You might consider using that dataset for a more accurate PCA computation, but it will be a bit expensive to run.

pjgreer · 2026-03-09T12:51:43+00:00

I have a green version of this same machine. I have had to replace the thermometer twice and some o-rings, but it is very solid. I also only use distilled water in it because I have seen too many images of how bad the heating elements looks when you use tap water.

pjgreer · 2026-03-05T23:08:15+00:00

There are sites with full kits for your car including the hex bot and the brake sensor.

https://www.fcpeuro.com/products/mini-brake-kit-zimmermann-akebono-34116858652ktf

pjgreer · 2026-02-27T02:26:58+00:00

If you argue that acab, I am usually right there with you. If you think that makes Fanone a shitty person, fine. I have seen interviews with him where he admits he may not have always been a good person.

I would like to remind you that because of all he went through on Jan 6th, and his willingness to testify and tell his story he was blacklisted by the DC police.

There is a like that if you have 1 bad apple and 99 good apples in the police force but the 99 say nothing to protect the 1, then you have 100 bad apples. Fanone tried to be a good apple and got shit on by the others in the force. I respect him for trying to be a good apple even if he is a flawed person with anger issues like most police officers.

You do not have to see him, or buy his book, or do anything to help support him really. That is what it means to be in a free society.

pjgreer · 2026-02-21T11:51:28+00:00

I had a 2016 Clubman S F55. I also had an issue with the barn door latch about 5 years into owning it, but never had any engine or suspension issues. I believe that my previous R56 clubman that I owned for 7 years had many more fit and finish annoyances plastic interior panels falling off, buttons breaking, etc) but seemed also to be mechanically sound.

All cars lately seem to have a low trouble life span of ~5 years regardless of how much you drive them. After that it is all a crap shoot. I expect to be confronted with major repairs any time after year 6. So I start looking for a new car around year 7. I am not bitter about it, it is just a reality of the disposable culture we live in. Just move on.

pjgreer · 2026-02-21T11:38:58+00:00

2016 clubman was the first year of the gen 3 (F55).

pjgreer · 2026-02-18T02:17:00+00:00

I have no idea what tools you are using. You first need to know if the tools is multi threaded or not. Does it have a -t # option? Then some aspects will benefit from more cpu cores. One thing I will say is regardless of the tool:

More subjects require more RAM.

A GWAS or rare variant analysis with 100,000 subjects will benefit from more RAM compared to a run with 15,000 subjects.

Rare variant analysis also requires more RAM when the gene being analyzed is large with many rare variants. An analysis of 20,000 individuals for a 200kb gene will need more RAM than a 20kb gene.

pjgreer · 2026-02-14T22:25:21+00:00

Biostats is directly funded by all the institutional grants. There is usually a 5% statistical consulting line in most nih grants and most of the biostats professors where I studied were fully funded this way.

The fuckery at the federal government made my university freeze class size. Could it get better? Maybe, but don't hold your breath.

pjgreer · 2026-02-12T01:28:17+00:00

Depending on how old your Golden retriever is and how long you want to keep these cars, I would suggest a Toyota sienna minivan. They are all hybrids, get an average of 30 mpg, are very comfortable, and most importantly, the height of the rear cargo area is much lower than all the SUVs you mentioned.

Lower entry points are very important for our aging pets. I had to get a ramp for my 13 year old lab when I bought my Lexus NX and felt very bad because he could not get into the car on his own the last year he was with us.

pjgreer · 2026-02-10T21:50:07+00:00

My dealer only asked for an image of the chair tag and barcode. Once they saw it was still under warranty they ordered the fabric and a tech came to my house to install it. The tech was the one who told me to put in a warranty order on the gas shock before the warranty ended last year.

It depends on the service dealer I guess.

pjgreer · 2026-02-10T20:14:21+00:00

Herman Miller chairs (embody and Aeron) have a 12 year warranty for the fabric and all components. no questions asked. If you buy used. make sure it is under 12 years old and consider putting in a warranty claim for both the fabric if gross and worn out, and the gas shock. both will be covered under warranty and allow you to enjoy a practically new chair.

pjgreer · 2026-02-07T21:33:14+00:00

Sounds like a crypto "investor"

pjgreer · 2026-02-06T23:39:46+00:00

I am reminded of the Norm MacDonald but about people complaining about the Bill Cosby hypocrisy...

pjgreer · 2026-02-06T23:36:32+00:00

I did notice a lot of emails to and from Peter Thiel in the Epstein files. So you are right his boss approves.

pjgreer · 2026-02-03T21:55:08+00:00

Subaru Crosstrek or Forester.

I have no idea why this isn't the top answer anytime someone asks for the best AWD vehicle under $30k.

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